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Galnt18 polypeptide N-acetylgalactosaminyltransferase 18 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293181, updated on 2-Nov-2024

Summary

Official Symbol
Galnt18provided by RGD
Official Full Name
polypeptide N-acetylgalactosaminyltransferase 18provided by RGD
Primary source
RGD:1309623
See related
EnsemblRapid:ENSRNOG00000017021 AllianceGenome:RGD:1309623
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Galntl4; RGD1309623
Summary
Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human GALNT18 (polypeptide N-acetylgalactosaminyltransferase 18). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 258.4), Kidney (RPKM 170.7) and 8 other tissues See more
Orthologs
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Genomic context

See Galnt18 in Genome Data Viewer
Location:
1q33
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (175027832..175338883, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (165593180..165904268, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (176296186..176607466, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 10-6-like Neighboring gene transfer RNA serine (anticodon GCU) 1 Neighboring gene uncharacterized LOC120099905 Neighboring gene uncharacterized LOC134485164 Neighboring gene uncharacterized LOC134485163

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC156692

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables polypeptide N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables polypeptide N-acetylgalactosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein O-linked glycosylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
polypeptide N-acetylgalactosaminyltransferase 18
Names
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
polypeptide N-acetylgalactosaminyltransferase-like 4
putative polypeptide N-acetylgalactosaminyltransferase-like protein 4
NP_001073353.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079884.1NP_001073353.1  polypeptide N-acetylgalactosaminyltransferase 18

    See identical proteins and their annotated locations for NP_001073353.1

    Status: PROVISIONAL

    Source sequence(s)
    BC128745
    UniProtKB/TrEMBL
    A0A8J8XFR5, A1A5P1, A6I851, E9PSI9
    Related
    ENSRNOP00000022984.6, ENSRNOT00000022984.8
    Conserved Domains (3) summary
    cd02510
    Location:157458
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:471598
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:469596
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    175027832..175338883 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)