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Gstp3 glutathione S-transferase pi 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293656, updated on 2-Nov-2024

Summary

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Official Symbol
Gstp3provided by RGD
Official Full Name
glutathione S-transferase pi 3provided by RGD
Primary source
RGD:1307603
See related
EnsemblRapid:ENSRNOG00000018287 AllianceGenome:RGD:1307603
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307603
Summary
Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 1404.7) See more
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Genomic context

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See Gstp3 in Genome Data Viewer
Location:
1q43
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (210785151..210787705, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (201355682..201358216, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (219309593..219312240, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483955 Neighboring gene NADH:ubiquinone oxidoreductase core subunit V1 Neighboring gene glutathione S-transferase pi 1 Neighboring gene calcium binding protein 2 Neighboring gene cyclin-dependent kinase 2 associated protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutathione transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Glutathione S-transferase P-like; glutathione S-transferase P-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134508.2 → NP_001127980.1  Glutathione S-transferase P-like isoform 2

    See identical proteins and their annotated locations for NP_001127980.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6HYR9, A6HYS0, D4A8S2
    Related
    ENSRNOP00000059097.1, ENSRNOT00000066691.3
    Conserved Domains (3) summary
    PTZ00057
    Location:6 → 158
    PTZ00057; glutathione s-transferase; Provisional
    cd03076
    Location:3 → 74
    GST_N_Pi; GST_N family, Class Pi subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...
    cl02776
    Location:84 → 166
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

  2. NM_001398780.1 → NP_001385709.1  Glutathione S-transferase P-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A0G2K4Q5
    Related
    ENSRNOP00000073133.2, ENSRNOT00000085439.3
    Conserved Domains (2) summary
    cd03076
    Location:3 → 74
    GST_N_Pi; GST_N family, Class Pi subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...
    cl02776
    Location:84 → 202
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    210785151..210787705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230737.3 → XP_006230799.1  glutathione S-transferase P-like isoform X1

    UniProtKB/TrEMBL
    A6HYS0
    Conserved Domains (3) summary
    COG0625
    Location:2 → 189
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cl00388
    Location:1 → 57
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    cl02776
    Location:67 → 185
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

  2. XM_039108270.2 → XP_038964198.1  glutathione S-transferase P-like isoform X2

    Conserved Domains (1) summary
    cl02776
    Location:1 → 111
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
Nucleotide Protein Strain
Heading Accession and Version

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