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Trpt1 tRNA phosphotransferase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293704, updated on 2-Nov-2024

Summary

Official Symbol
Trpt1provided by RGD
Official Full Name
tRNA phosphotransferase 1provided by RGD
Primary source
RGD:1310831
See related
EnsemblRapid:ENSRNOG00000023023 AllianceGenome:RGD:1310831
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tpt1h
Summary
Predicted to enable tRNA 2'-phosphotransferase activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to act upstream of or within regulation of protein kinase activity. Orthologous to human TRPT1 (tRNA phosphotransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 132.8), Spleen (RPKM 114.3) and 9 other tissues See more
Orthologs
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Genomic context

See Trpt1 in Genome Data Viewer
Location:
1q43
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (213615503..213620502)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (204186295..204191294)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (222250995..222255994)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene vascular endothelial growth factor B Neighboring gene DnaJ heat shock protein family (Hsp40) member C4 Neighboring gene nudix hydrolase 22 Neighboring gene FERM domain containing kindlin 3 Neighboring gene uncharacterized LOC120099981 Neighboring gene stress-induced phosphoprotein 1 Neighboring gene mono-ADP ribosylhydrolase 1 Neighboring gene fibronectin leucine rich transmembrane protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
tRNA 2'-phosphotransferase 1
Names
tRNA splicing 2' phosphotransferase 1 homolog
NP_001099801.1
XP_006230823.1
XP_063142955.1
XP_063142957.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106331.1NP_001099801.1  tRNA 2'-phosphotransferase 1

    See identical proteins and their annotated locations for NP_001099801.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473953
    UniProtKB/TrEMBL
    A6HZM9, D3ZBT6
    Related
    ENSRNOP00000031211.4, ENSRNOT00000031458.6
    Conserved Domains (1) summary
    pfam01885
    Location:21198
    PTS_2-RNA; RNA 2'-phosphotransferase, Tpt1 / KptA family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    213615503..213620502
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230761.5XP_006230823.1  tRNA 2'-phosphotransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_006230823.1

    UniProtKB/TrEMBL
    A6HZM9, D3ZBT6
    Conserved Domains (1) summary
    pfam01885
    Location:21198
    PTS_2-RNA; RNA 2'-phosphotransferase, Tpt1 / KptA family
  2. XM_063286885.1XP_063142955.1  tRNA 2'-phosphotransferase 1 isoform X2

  3. XM_063286887.1XP_063142957.1  tRNA 2'-phosphotransferase 1 isoform X2