Plaat5 phospholipase A and acyltransferase 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Plaat5provided by RGD
Official Full Name: phospholipase A and acyltransferase 5provided by RGD
Primary source: RGD:1308376
See related: EnsemblRapid:ENSRNOG00000023528 AllianceGenome:RGD:1308376
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: iNAT; HRSL5; RLP-1; Hrasls5; RGD1308376
Summary: Enables N-acyltransferase activity. Acts upstream of or within N-acylphosphatidylethanolamine metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human PLAAT5 (phospholipase A and acyltransferase 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward (RPKM 1135.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 1q43

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (214276553..214307600)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (204847600..204878456)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (222907159..222937643)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Expression was detected primarily in the spermatocytes in the maturing rat testis. The Hrasls5 gene product might function as a tumor suppressor as well as in spermatogenesis, as deduced from its amino acid sequence.
Title: Expression of the Ha-ras suppressor family member 5 gene in the maturing rat testis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables N-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables N-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables N-acyltransferase activity	ISO Inferred from Sequence Orthology more info
enables phosphatidylserine 1-acylhydrolase activity	IEA Inferred from Electronic Annotation more info
enables phospholipase A1 activity	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipase A1 activity	IEA Inferred from Electronic Annotation more info
enables phospholipase A1 activity	ISO Inferred from Sequence Orthology more info
enables phospholipase A2 activity	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipase A2 activity	IEA Inferred from Electronic Annotation more info
enables phospholipase A2 activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in N-acylphosphatidylethanolamine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within N-acylphosphatidylethanolamine metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in N-acylphosphatidylethanolamine metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within N-acylphosphatidylethanolamine metabolic process	ISO Inferred from Sequence Orthology more info
involved_in N-acylphosphatidylethanolamine metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: phospholipase A and acyltransferase 5

Names: Ca(2+)-independent N-acyltransferase; H-rev107-like protein 5; HRAS-like suppressor 5; HRAS-like suppressor family, member 5; LRAT-like protein-1

NP_001034096.1

EC 3.1.1.32

EC 3.1.1.4

XP_006230830.1

EC 3.1.1.32

EC 3.1.1.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.