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Poc5 POC5 centriolar protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 294667, updated on 2-Nov-2024

Summary

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Official Symbol
Poc5provided by RGD
Official Full Name
POC5 centriolar proteinprovided by RGD
Primary source
RGD:1310597
See related
EnsemblRapid:ENSRNOG00000018193 AllianceGenome:RGD:1310597
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310597
Summary
Predicted to be involved in eye photoreceptor cell development. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in centrosome and photoreceptor connecting cilium. Orthologous to human POC5 (POC5 centriolar protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 53.7), Thymus (RPKM 47.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Poc5 in Genome Data Viewer
Location:
2q12
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (29454392..29483468)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (27719745..27748805)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (27000303..27030646)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene nucleophosmin 1, pseudogene 10 Neighboring gene metal response element binding transcription factor 2, pseudogene 1 Neighboring gene ankyrin repeat and death domain containing 1B Neighboring gene DNA polymerase kappa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
  2. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC114560

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in eye photoreceptor cell development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in photoreceptor connecting cilium IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
centrosomal protein POC5
Names
POC5 centriolar protein homolog
protein of centriole 5
proteome of centriole 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025647.1 → NP_001020818.1  centrosomal protein POC5

    See identical proteins and their annotated locations for NP_001020818.1

    Status: VALIDATED

    Source sequence(s)
    BC097489
    UniProtKB/Swiss-Prot
    Q4V891
    Related
    ENSRNOP00000103023.1, ENSRNOT00000126447.1
    Conserved Domains (2) summary
    COG1196
    Location:175 → 354
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK07003
    Location:371 → 543
    PRK07003; DNA polymerase III subunits gamma and tau; Validated

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    29454392..29483468
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039101919.2 → XP_038957847.1  centrosomal protein POC5 isoform X1

    Related
    ENSRNOP00000070872.2, ENSRNOT00000087418.3
    Conserved Domains (1) summary
    PRK07003
    Location:271 → 443
    PRK07003; DNA polymerase III subunit gamma/tau
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V891.1 GenPept UniProtKB/Swiss-Prot:Q4V891

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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