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Ankrd50 ankyrin repeat domain containing 50 [ Rattus norvegicus (Norway rat) ]

Gene ID: 294988, updated on 10-Jul-2024

Summary

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Official Symbol
Ankrd50provided by RGD
Official Full Name
ankyrin repeat domain containing 50provided by RGD
Primary source
RGD:1311665
See related
EnsemblRapid:ENSRNOG00000010534 AllianceGenome:RGD:1311665
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311665
Summary
Predicted to be involved in endocytic recycling. Orthologous to human ANKRD50 (ankyrin repeat domain 50). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 174.9), Heart (RPKM 122.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ankrd50 in Genome Data Viewer
Location:
2q25
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (123394311..123428788, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (121466275..121500758, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (125289071..125323527, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S6, pseudogene 3 Neighboring gene ribosomal protein L23A like 3 Neighboring gene uncharacterized LOC103691533 Neighboring gene uncharacterized LOC120100576

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling. McGough IJ, et al. J Cell Sci, 2014 Nov 15. PMID 25278552, Free PMC Article
  2. Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth. Mertz J, et al. Mol Cell Proteomics, 2015 Jul. PMID 25931508, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in endocytic recycling ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 50
Names
ankrin repeat domain 50
ankyrin repeat domain 50

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191606.1 → NP_001178535.1  ankyrin repeat domain-containing protein 50

    See identical proteins and their annotated locations for NP_001178535.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    F1LWB9
    Related
    ENSRNOP00000043031.4, ENSRNOT00000045837.7
    Conserved Domains (4) summary
    PHA02876
    Location:763 → 1102
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:625 → 907
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:676 → 707
    ANK; ANK repeat [structural motif]
    pfam13191
    Location:23 → 195
    AAA_16; AAA ATPase domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    123394311..123428788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008760922.4 → XP_008759144.1  ankyrin repeat domain-containing protein 50 isoform X1

    See identical proteins and their annotated locations for XP_008759144.1

    UniProtKB/TrEMBL
    F1LWB9
    Conserved Domains (4) summary
    PHA02876
    Location:763 → 1102
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:625 → 907
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:676 → 707
    ANK; ANK repeat [structural motif]
    pfam13191
    Location:23 → 195
    AAA_16; AAA ATPase domain

  2. XM_008760921.4 → XP_008759143.1  ankyrin repeat domain-containing protein 50 isoform X1

    See identical proteins and their annotated locations for XP_008759143.1

    UniProtKB/TrEMBL
    F1LWB9
    Conserved Domains (4) summary
    PHA02876
    Location:763 → 1102
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:625 → 907
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:676 → 707
    ANK; ANK repeat [structural motif]
    pfam13191
    Location:23 → 195
    AAA_16; AAA ATPase domain

  3. XM_008760920.4 → XP_008759142.1  ankyrin repeat domain-containing protein 50 isoform X1

    See identical proteins and their annotated locations for XP_008759142.1

    UniProtKB/TrEMBL
    F1LWB9
    Conserved Domains (4) summary
    PHA02876
    Location:763 → 1102
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:625 → 907
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:676 → 707
    ANK; ANK repeat [structural motif]
    pfam13191
    Location:23 → 195
    AAA_16; AAA ATPase domain
Nucleotide Protein Strain
Heading Accession and Version

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