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S100vp S100 calcium-binding protein, ventral prostate [ Rattus norvegicus (Norway rat) ]

Gene ID: 295176, updated on 2-Nov-2024

Summary

Official Symbol
S100vpprovided by RGD
Official Full Name
S100 calcium-binding protein, ventral prostateprovided by RGD
Primary source
RGD:631357
See related
EnsemblRapid:ENSRNOG00000028310 AllianceGenome:RGD:631357
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
S100RVP
Summary
Enables calcium ion binding activity. Involved in intracellular calcium ion homeostasis and response to testosterone. Predicted to be active in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 1.2) See more
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Genomic context

See S100vp in Genome Data Viewer
Location:
2q34
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (179094066..179097417, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (176748273..176751624, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (190628525..190631821)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485741 Neighboring gene S100 calcium binding protein A7 like 2 Neighboring gene peptidoglycan recognition protein 3, pseudogene 1 Neighboring gene choline-phosphate cytidylyltransferase A-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables S100 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables calcium-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in intracellular calcium ion homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in response to testosterone IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
S100 calcium-binding protein, ventral prostate

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176076.4NP_788265.1  S100 calcium-binding protein, ventral prostate

    See identical proteins and their annotated locations for NP_788265.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A6KMS0, F7FGS5, Q80VT8
    Related
    ENSRNOP00000023564.2, ENSRNOT00000023564.5
    Conserved Domains (1) summary
    cl08302
    Location:685
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    179094066..179097417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)