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Gpatch4 G patch domain containing 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295228, updated on 2-Nov-2024

Summary

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Official Symbol
Gpatch4provided by RGD
Official Full Name
G patch domain containing 4provided by RGD
Primary source
RGD:1311086
See related
EnsemblRapid:ENSRNOG00000018969 AllianceGenome:RGD:1311086
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311086
Summary
Predicted to enable nucleic acid binding activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human GPATCH4 (G-patch domain containing 4 (gene/pseudogene)). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 40.4), Brain (RPKM 35.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gpatch4 in Genome Data Viewer
Location:
2q34
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (175797503..175816547)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173499700..173520346)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187404731..187424047)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene brevican Neighboring gene hyaluronan and proteoglycan link protein 2 Neighboring gene NAD(P)HX epimerase Neighboring gene tetratricopeptide repeat domain 24

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
G patch domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024979.1 → NP_001020150.1  G patch domain-containing protein 4

    See identical proteins and their annotated locations for NP_001020150.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093381
    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647
    Related
    ENSRNOP00000053762.3, ENSRNOT00000056923.4
    Conserved Domains (1) summary
    pfam01585
    Location:8 → 55
    G-patch; G-patch domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    175797503..175816547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281605.1 → XP_063137675.1  G patch domain-containing protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647

  2. XM_063281602.1 → XP_063137672.1  G patch domain-containing protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647

  3. XM_063281601.1 → XP_063137671.1  G patch domain-containing protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647

  4. XM_063281600.1 → XP_063137670.1  G patch domain-containing protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647

  5. XM_063281603.1 → XP_063137673.1  G patch domain-containing protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647

  6. XM_063281604.1 → XP_063137674.1  G patch domain-containing protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647

  7. XM_008761132.4 → XP_008759354.1  G patch domain-containing protein 4 isoform X1

    See identical proteins and their annotated locations for XP_008759354.1

    UniProtKB/Swiss-Prot
    Q566R3
    UniProtKB/TrEMBL
    A6J647
    Conserved Domains (1) summary
    pfam01585
    Location:8 → 55
    G-patch; G-patch domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q566R3.1 GenPept UniProtKB/Swiss-Prot:Q566R3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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