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Krtcap2 keratinocyte associated protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295243, updated on 17-Aug-2024

Summary

Official Symbol
Krtcap2provided by RGD
Official Full Name
keratinocyte associated protein 2provided by RGD
Primary source
RGD:1308413
See related
EnsemblRapid:ENSRNOG00000020542 AllianceGenome:RGD:1308413
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable enzyme activator activity. Predicted to be involved in protein N-linked glycosylation via arginine. Predicted to be integral component of membrane. Predicted to be part of oligosaccharyltransferase complex. Orthologous to human KRTCAP2 (keratinocyte associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 134.2), Lung (RPKM 109.0) and 9 other tissues See more
Orthologs
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Genomic context

Location:
2q34
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176952167..176956163)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174654409..174658405)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188561548..188565544)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene microRNA 92b Neighboring gene mucin 1, cell surface associated Neighboring gene tripartite motif-containing 46 Neighboring gene solute carrier family 50 member 1 Neighboring gene dolichyl-phosphate mannosyltransferase subunit 3, regulatory

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables enzyme activator activity IEA
Inferred from Electronic Annotation
more info
 
enables enzyme activator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein N-linked glycosylation via arginine IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein N-linked glycosylation via arginine IEA
Inferred from Electronic Annotation
more info
 
involved_in protein N-linked glycosylation via arginine ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of oligosaccharyltransferase complex IEA
Inferred from Electronic Annotation
more info
 
part_of oligosaccharyltransferase complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
keratinocyte-associated protein 2
Names
KCP-2
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2
oligosaccharyl transferase subunit KCP2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106444.1NP_001099914.1  keratinocyte-associated protein 2

    See identical proteins and their annotated locations for NP_001099914.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473976
    UniProtKB/TrEMBL
    A0A8L2QZG2, A6J6D6, F1LMZ2
    Related
    ENSRNOP00000027867.6, ENSRNOT00000027867.8
    Conserved Domains (1) summary
    pfam09775
    Location:1109
    Keratin_assoc; Keratinocyte-associated protein 2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    176952167..176956163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)