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Ctnnbl1 catenin, beta like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296320, updated on 28-Oct-2024

Summary

Official Symbol
Ctnnbl1provided by RGD
Official Full Name
catenin, beta like 1provided by RGD
Primary source
RGD:1563558
See related
EnsemblRapid:ENSRNOG00000012021 AllianceGenome:RGD:1563558
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of apoptotic process and somatic diversification of immunoglobulins. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of Prp19 complex and spliceosomal complex. Human ortholog(s) of this gene implicated in colorectal cancer; morbid obesity; and primary immunodeficiency disease. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Thymus (RPKM 166.0), Adrenal (RPKM 118.6) and 9 other tissues See more
Orthologs
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Genomic context

See Ctnnbl1 in Genome Data Viewer
Location:
3q42
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (166807899..166968932)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (146387940..146548987)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (154212245..154373170)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350620 Neighboring gene uncharacterized LOC120101772 Neighboring gene mitochondrial pyruvate carrier 1-like, pseudogene 3 Neighboring gene uncharacterized LOC134486468 Neighboring gene V-set and transmembrane domain containing 2 like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables enzyme binding IEA
Inferred from Electronic Annotation
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in somatic diversification of immunoglobulins IEA
Inferred from Electronic Annotation
more info
 
involved_in somatic diversification of immunoglobulins ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of Prp19 complex IEA
Inferred from Electronic Annotation
more info
 
part_of Prp19 complex ISO
Inferred from Sequence Orthology
more info
 
part_of Prp19 complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
part_of spliceosomal complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
beta-catenin-like protein 1
Names
NAP
beta catenin-like 1
nuclear-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024870.1NP_001020041.1  beta-catenin-like protein 1

    See identical proteins and their annotated locations for NP_001020041.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097352
    UniProtKB/Swiss-Prot
    Q4V8K2
    UniProtKB/TrEMBL
    A0A8L2QUN4, A6JWU4
    Related
    ENSRNOP00000060192.4, ENSRNOT00000066808.5
    Conserved Domains (1) summary
    pfam08216
    Location:57162
    CTNNBL; Catenin-beta-like, Arm-motif containing nuclear

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    166807899..166968932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039104624.2XP_038960552.1  beta-catenin-like protein 1 isoform X1