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Oser1 oxidative stress responsive serine-rich 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296346, updated on 10-Oct-2024

Summary

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Official Symbol
Oser1provided by RGD
Official Full Name
oxidative stress responsive serine-rich 1provided by RGD
Primary source
RGD:1303142
See related
EnsemblRapid:ENSRNOG00000008297 AllianceGenome:RGD:1303142
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
osr1; Perit1; RGD1303142
Summary
Involved in cellular response to hydrogen peroxide. Orthologous to human OSER1 (oxidative stress responsive serine rich 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 274.1), Lung (RPKM 101.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Oser1 in Genome Data Viewer
Location:
3q42
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (172486417..172504607, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (152066975..152085180, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (159784131..159802923, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene TOX high mobility group box family member 2 Neighboring gene junctophilin 2 Neighboring gene uncharacterized LOC120101779 Neighboring gene ganglioside-induced differentiation-associated protein 1-like 1 Neighboring gene uncharacterized LOC103691964 Neighboring gene fat storage-inducing transmembrane protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Cardiac myocyte gene expression profiling during H2O2-induced apoptosis. Clerk A, et al. Physiol Genomics, 2007 Apr 24. PMID 17148688
  2. Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses. Vorontsova I, et al. Invest Ophthalmol Vis Sci, 2014 Dec 16. PMID 25515571, Free PMC Article
  3. Gene expression analysis in response to lung toxicants: I. Sequencing and microarray development. Shultz MA, et al. Am J Respir Cell Mol Biol, 2004 Mar. PMID 12947022
  4. A genomic analysis of rat proteases and protease inhibitors. Puente XS, et al. Genome Res, 2004 Apr. PMID 15060002, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cellular response to hydrogen peroxide IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to hydrogen peroxide IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
oxidative stress-responsive serine-rich protein 1
Names
oxidative stress responsive 1
oxidative stress-responsive protein 1
peroxide-inducible transcript 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430198.1 → NP_001417127.1  oxidative stress-responsive serine-rich protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q703I1

  2. NM_001430199.1 → NP_001417128.1  oxidative stress-responsive serine-rich protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q703I1

  3. NM_001430200.1 → NP_001417129.1  oxidative stress-responsive serine-rich protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q703I1

  4. NM_201560.3 → NP_963854.1  oxidative stress-responsive serine-rich protein 1

    See identical proteins and their annotated locations for NP_963854.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q703I1
    UniProtKB/TrEMBL
    A0A8L2Q532
    Related
    ENSRNOP00000011610.5, ENSRNOT00000011610.7
    Conserved Domains (1) summary
    pfam05604
    Location:1 → 175
    DUF776; Protein of unknown function (DUF776)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    172486417..172504607 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017591608.3 → XP_017447097.1  oxidative stress-responsive serine-rich protein 1 isoform X1

    Conserved Domains (1) summary
    pfam05604
    Location:1 → 175
    DUF776; Protein of unknown function (DUF776)

  2. XM_039104628.2 → XP_038960556.1  oxidative stress-responsive serine-rich protein 1 isoform X1

    Conserved Domains (1) summary
    pfam05604
    Location:1 → 175
    DUF776; Protein of unknown function (DUF776)

  3. XM_063283388.1 → XP_063139458.1  oxidative stress-responsive serine-rich protein 1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q703I1.1 GenPept UniProtKB/Swiss-Prot:Q703I1

Gene LinkOut

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