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Tpd52l2 TPD52 like 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296480, updated on 2-Nov-2024

Summary

Official Symbol
Tpd52l2provided by RGD
Official Full Name
TPD52 like 2provided by RGD
Primary source
RGD:735167
See related
EnsemblRapid:ENSRNOG00000080504 AllianceGenome:RGD:735167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable protein homodimerization activity. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human TPD52L2 (TPD52 like 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 161.8), Muscle (RPKM 155.2) and 9 other tissues See more
Orthologs
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Genomic context

See Tpd52l2 in Genome Data Viewer
Location:
3q43
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (188972321..188995721)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (168598449..168618201)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (176989333..177009425)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 46 Neighboring gene RNA, U6 small nuclear 663 Neighboring gene uncharacterized LOC120101834 Neighboring gene uncharacterized LOC102548047 Neighboring gene abhydrolase domain containing 16B Neighboring gene ribosomal protein L34-like2 Neighboring gene DnaJ heat shock protein family (Hsp40) member C5 Neighboring gene uridine-cytidine kinase 1-like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC73020

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
tumor protein D54
Names
tumor protein D52-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431560.1NP_001418489.1  tumor protein D54 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6KM05
  2. NM_001431561.1NP_001418490.1  tumor protein D54 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
  3. NM_001431562.1NP_001418491.1  tumor protein D54 isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
  4. NM_001431563.1NP_001418492.1  tumor protein D54 isoform 5

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6KM07
  5. NM_001431564.1NP_001418493.1  tumor protein D54 isoform 6

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
  6. NM_001431565.1NP_001418494.1  tumor protein D54 isoform 7

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
  7. NM_001431566.1NP_001418495.1  tumor protein D54 isoform 8

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
  8. NM_001431567.1NP_001418496.1  tumor protein D54 isoform 9

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6KM00
  9. NM_001431568.1NP_001418497.1  tumor protein D54 isoform 10

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
  10. NM_198744.3NP_942039.1  tumor protein D54 isoform 2

    See identical proteins and their annotated locations for NP_942039.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q6PCT3
    UniProtKB/TrEMBL
    A6KM06, A6KM08
    Conserved Domains (1) summary
    pfam04201
    Location:55211
    TPD52; tumor protein D52 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    188972321..188995721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235761.4XP_006235823.1  tumor protein D54 isoform X13

    See identical proteins and their annotated locations for XP_006235823.1

    UniProtKB/TrEMBL
    A6KM02, A6KM08
    Conserved Domains (1) summary
    pfam04201
    Location:55177
    TPD52; tumor protein D52 family
  2. XM_006235759.5XP_006235821.1  tumor protein D54 isoform X7

    Related
    ENSRNOP00000108826.1, ENSRNOT00000141925.1
    Conserved Domains (1) summary
    pfam04201
    Location:55197
    TPD52; tumor protein D52 family
  3. XM_039104697.2XP_038960625.1  tumor protein D54 isoform X1

    Related
    ENSRNOP00000080130.2, ENSRNOT00000114740.2
    Conserved Domains (1) summary
    pfam04201
    Location:55221
    TPD52; tumor protein D52 family
  4. XM_006235754.5XP_006235816.1  tumor protein D54 isoform X2

    Conserved Domains (1) summary
    pfam04201
    Location:55220
    TPD52; tumor protein D52 family
  5. XM_039104698.2XP_038960626.1  tumor protein D54 isoform X3

  6. XM_063283451.1XP_063139521.1  tumor protein D54 isoform X18

  7. XM_063283448.1XP_063139518.1  tumor protein D54 isoform X14

  8. XM_063283449.1XP_063139519.1  tumor protein D54 isoform X16

  9. XM_017591623.3XP_017447112.1  tumor protein D54 isoform X19

  10. XM_039104700.2XP_038960628.1  tumor protein D54 isoform X6

    UniProtKB/TrEMBL
    A6KM08
    Conserved Domains (1) summary
    pfam04201
    Location:32198
    TPD52; tumor protein D52 family
  11. XM_063283446.1XP_063139516.1  tumor protein D54 isoform X8

    UniProtKB/TrEMBL
    A6KM01
  12. XM_063283447.1XP_063139517.1  tumor protein D54 isoform X11

  13. XM_039104699.2XP_038960627.1  tumor protein D54 isoform X4

    Conserved Domains (1) summary
    pfam04201
    Location:55201
    TPD52; tumor protein D52 family
  14. XM_039104702.2XP_038960630.1  tumor protein D54 isoform X12

    Conserved Domains (1) summary
    pfam04201
    Location:32188
    TPD52; tumor protein D52 family
  15. XM_006235757.5XP_006235819.1  tumor protein D54 isoform X5

    See identical proteins and their annotated locations for XP_006235819.1

    UniProtKB/TrEMBL
    A6KM04
    Conserved Domains (1) summary
    pfam04201
    Location:55200
    TPD52; tumor protein D52 family
  16. XM_039104701.2XP_038960629.1  tumor protein D54 isoform X9

    Conserved Domains (1) summary
    pfam04201
    Location:55192
    TPD52; tumor protein D52 family
  17. XM_008762500.3XP_008760722.1  tumor protein D54 isoform X17

    UniProtKB/TrEMBL
    A6KM08
    Conserved Domains (1) summary
    pfam04201
    Location:32154
    TPD52; Tumour protein D52 family
  18. XM_006235760.5XP_006235822.1  tumor protein D54 isoform X10

    See identical proteins and their annotated locations for XP_006235822.1

    UniProtKB/TrEMBL
    A6KM03, A6KM08
    Conserved Domains (1) summary
    pfam04201
    Location:55191
    TPD52; tumor protein D52 family
  19. XM_039104703.2XP_038960631.1  tumor protein D54 isoform X15

    Conserved Domains (1) summary
    pfam04201
    Location:32174
    TPD52; tumor protein D52 family