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Slc2a6 solute carrier family 2 member 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296600, updated on 2-Nov-2024

Summary

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Official Symbol
Slc2a6provided by RGD
Official Full Name
solute carrier family 2 member 6provided by RGD
Primary source
RGD:1309317
See related
EnsemblRapid:ENSRNOG00000005900 AllianceGenome:RGD:1309317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in regulation of glycolytic process. Predicted to be located in lysosomal membrane. Orthologous to human SLC2A6 (solute carrier family 2 member 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 93.8), Adrenal (RPKM 72.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc2a6 in Genome Data Viewer
Location:
3p12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (30746472..30753287, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (10348395..10355208, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (5567729..5575144, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene REX4 homolog, 3'-5' exonuclease Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 13 Neighboring gene uncharacterized LOC102548484 Neighboring gene calcium channel flower domain containing 1 Neighboring gene myomaker, myoblast fusion factor Neighboring gene ADAMTS-like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates glycolysis in macrophages. Maedera S, et al. FEBS Lett, 2019 Jan. PMID 30431159
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
NOT enables D-glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
NOT involved_in D-glucose transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of glycolytic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
solute carrier family 2, facilitated glucose transporter member 6
Names
solute carrier family 2 (facilitated glucose transporter), member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429160.1 → NP_001416089.1  solute carrier family 2, facilitated glucose transporter member 6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

  2. NM_001429161.1 → NP_001416090.1  solute carrier family 2, facilitated glucose transporter member 6 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

  3. NM_001429162.1 → NP_001416091.1  solute carrier family 2, facilitated glucose transporter member 6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    30746472..30753287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063283473.1 → XP_063139543.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X2

    Related
    ENSRNOP00000105485.1, ENSRNOT00000150537.1

  2. XM_063283475.1 → XP_063139545.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X4

  3. XM_063283474.1 → XP_063139544.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X3

  4. XM_063283472.1 → XP_063139542.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X1

  5. XM_063283476.1 → XP_063139546.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X5

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001106562.1: Suppressed sequence

    Description
    NM_001106562.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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