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Tmem176a transmembrane protein 176A [ Rattus norvegicus (Norway rat) ]

Gene ID: 297077, updated on 2-Nov-2024

Summary

Official Symbol
Tmem176aprovided by RGD
Official Full Name
transmembrane protein 176Aprovided by RGD
Primary source
RGD:1310725
See related
EnsemblRapid:ENSRNOG00000023708 AllianceGenome:RGD:1310725
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310725; 0610011i04rik
Summary
Predicted to act upstream of or within negative regulation of dendritic cell differentiation. Predicted to be located in membrane. Orthologous to human TMEM176A (transmembrane protein 176A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 543.8), Spleen (RPKM 456.2) and 9 other tissues See more
Orthologs
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Genomic context

See Tmem176a in Genome Data Viewer
Location:
4q24
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (79101946..79109499)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (77774940..77778620)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (78458735..78462415)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene GTPase, IMAP family member 1 Neighboring gene GTPase, IMAP family member 5 Neighboring gene transmembrane protein 176B Neighboring gene amine oxidase, copper containing 1 Neighboring gene DAB2 interacting protein, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
transmembrane protein 176A
Names
hepatocellular carcinoma-associated antigen 112

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039008.1NP_001034097.1  transmembrane protein 176A

    See identical proteins and their annotated locations for NP_001034097.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098714
    UniProtKB/Swiss-Prot
    Q4G068
    UniProtKB/TrEMBL
    A6K0J1
    Conserved Domains (1) summary
    pfam04103
    Location:63223
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    79101946..79109499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063285768.1XP_063141838.1  transmembrane protein 176A isoform X1

    Related
    ENSRNOP00000048649.3, ENSRNOT00000049891.6
  2. XM_063285769.1XP_063141839.1  transmembrane protein 176A isoform X2

    UniProtKB/Swiss-Prot
    Q4G068
    UniProtKB/TrEMBL
    A6K0J1