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Pnisr PNN interacting serine and arginine rich protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 297942, updated on 2-Nov-2024

Summary

Official Symbol
Pnisrprovided by RGD
Official Full Name
PNN interacting serine and arginine rich proteinprovided by RGD
Primary source
RGD:1307395
See related
EnsemblRapid:ENSRNOG00000008782 AllianceGenome:RGD:1307395
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sfrs18; Srsf18; RGD1307395
Summary
Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in nuclear speck and presynaptic active zone. Orthologous to human PNISR (PNN interacting serine and arginine rich protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 340.1), Brain (RPKM 271.9) and 9 other tissues See more
Orthologs
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Genomic context

See Pnisr in Genome Data Viewer
Location:
5q21
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (40190214..40219619)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (35395965..35422852)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (35991028..36017952)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478949 Neighboring gene ubiquitin specific peptidase 45 Neighboring gene large ribosomal subunit protein eL30-like Neighboring gene lysine acetyltransferase 2B, pseudogene 1 Neighboring gene coenzyme Q3 methyltransferase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC109235

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in presynaptic active zone IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
arginine/serine-rich protein PNISR
Names
PNN-interacting serine/arginine-rich protein
serine/arginine-rich splicing factor 18
splicing factor, arginine/serine-rich 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025274.2NP_001020445.2  arginine/serine-rich protein PNISR

    See identical proteins and their annotated locations for NP_001020445.2

    Status: PROVISIONAL

    Source sequence(s)
    CH473962
    UniProtKB/TrEMBL
    A6IIF0, A6IIF1, F1MAQ8
    Related
    ENSRNOP00000057854.3, ENSRNOT00000061139.6
    Conserved Domains (1) summary
    pfam15996
    Location:223380
    PNISR; Arginine/serine-rich protein PNISR

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    40190214..40219619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063287296.1XP_063143366.1  arginine/serine-rich protein PNISR isoform X2

  2. XM_063287297.1XP_063143367.1  arginine/serine-rich protein PNISR isoform X3

  3. XM_063287295.1XP_063143365.1  arginine/serine-rich protein PNISR isoform X1

RNA

  1. XR_010066349.1 RNA Sequence