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Dmac1 distal membrane arm assembly component 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298147, updated on 2-Nov-2024

Summary

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Official Symbol
Dmac1provided by RGD
Official Full Name
distal membrane arm assembly component 1provided by RGD
Primary source
RGD:1309148
See related
EnsemblRapid:ENSRNOG00000023946 AllianceGenome:RGD:1309148
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tmem261; RGD1309148
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Orthologous to human DMAC1 (distal membrane arm assembly component 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 189.2), Muscle (RPKM 187.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Dmac1 in Genome Data Viewer
Location:
5q31
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (94288900..94290053, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (89241173..89243793, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (92038050..92039146, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134487072 Neighboring gene vomeronasal 2 receptor, pseudogene 76 Neighboring gene uncharacterized LOC134486942 Neighboring gene eukaryotic translation elongation factor 1 gamma, pseudogene 16 Neighboring gene malate dehydrogenase 2, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Stroud DA, et al. Nature, 2016 Oct 6. PMID 27626371
  2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
distal membrane-arm assembly complex protein 1
Names
distal membrane arm assembly complex 1
transmembrane protein 261
transmembrane protein C9orf123 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206675.1 → NP_001193604.1  distal membrane-arm assembly complex protein 1

    See identical proteins and their annotated locations for NP_001193604.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A6J819, D4AEL3
    Related
    ENSRNOP00000029921.5, ENSRNOT00000031852.7
    Conserved Domains (1) summary
    pfam15055
    Location:45 → 91
    DUF4536; Domain of unknown function (DUF4536)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    94288900..94290053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039109504.2 → XP_038965432.1  distal membrane-arm assembly complex protein 1 isoform X1

    UniProtKB/TrEMBL
    A6J818
    Conserved Domains (1) summary
    pfam15055
    Location:45 → 62
    DUF4536; Domain of unknown function (DUF4536)
Nucleotide Protein Strain
Heading Accession and Version

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