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Bnc2 basonuclin zinc finger protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298189, updated on 2-Nov-2024

Summary

Official Symbol
Bnc2provided by RGD
Official Full Name
basonuclin zinc finger protein 2provided by RGD
Primary source
RGD:1310694
See related
EnsemblRapid:ENSRNOG00000006553 AllianceGenome:RGD:1310694
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable rDNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including endochondral bone growth; roof of mouth development; and tongue development. Predicted to be located in chromatin and nucleoplasm. Predicted to be active in nucleus. Orthologous to human BNC2 (basonuclin zinc finger protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Kidney (RPKM 55.8), Uterus (RPKM 48.5) and 7 other tissues See more
Orthologs
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Genomic context

See Bnc2 in Genome Data Viewer
Location:
5q31
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (103724934..104061890, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (98679071..99016044, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (102407508..102807389, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC108350993 Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC103692399

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables rDNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within endochondral bone growth ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within mesenchyme development ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
NOT acts_upstream_of_or_within regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within roof of mouth development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within tongue development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger protein basonuclin-2
Names
basonuclin 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106666.4NP_001100136.1  zinc finger protein basonuclin-2 isoform 1

    See identical proteins and their annotated locations for NP_001100136.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A8I5ZMQ2, A6J853, D3ZZ22
    Related
    ENSRNOP00000107024.1, ENSRNOT00000133529.1
    Conserved Domains (1) summary
    sd00017
    Location:10441065
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001415824.2NP_001402753.1  zinc finger protein basonuclin-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    Related
    ENSRNOP00000112129.1, ENSRNOT00000132122.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    103724934..104061890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)