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Lrrc42 leucine rich repeat containing 42 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298309, updated on 10-Jul-2024

Summary

Official Symbol
Lrrc42provided by RGD
Official Full Name
leucine rich repeat containing 42provided by RGD
Primary source
RGD:1308919
See related
EnsemblRapid:ENSRNOG00000009983 AllianceGenome:RGD:1308919
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308919
Summary
Orthologous to human LRRC42 (leucine rich repeat containing 42). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 247.9), Lung (RPKM 91.8) and 9 other tissues See more
Orthologs
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Genomic context

See Lrrc42 in Genome Data Viewer
Location:
5q34
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (127243484..127264599, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (122014678..122035792, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (126835170..126856283, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A N-terminal and central domain containing 2 Neighboring gene transmembrane protein 59 Neighboring gene low density lipoprotein receptor class A domain containing 1 Neighboring gene intraflagellar transport 25 Neighboring gene iodothyronine deiodinase 1 Neighboring gene uncharacterized LOC134486960

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
leucine-rich repeat-containing protein 42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025653.1NP_001020824.1  leucine-rich repeat-containing protein 42

    See identical proteins and their annotated locations for NP_001020824.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098685
    UniProtKB/Swiss-Prot
    Q4KM95
    UniProtKB/TrEMBL
    A6JYR1, A6JYR2
    Related
    ENSRNOP00000013575.4, ENSRNOT00000013575.8
    Conserved Domains (2) summary
    sd00034
    Location:150174
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl39015
    Location:167272
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    127243484..127264599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006238503.5XP_006238565.1  leucine-rich repeat-containing protein 42 isoform X1

    See identical proteins and their annotated locations for XP_006238565.1

    UniProtKB/Swiss-Prot
    Q4KM95
    UniProtKB/TrEMBL
    A6JYR1, A6JYR2
    Conserved Domains (2) summary
    sd00034
    Location:150174
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl39015
    Location:167272
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
  2. XM_039109553.2XP_038965481.1  leucine-rich repeat-containing protein 42 isoform X1

    UniProtKB/Swiss-Prot
    Q4KM95
    UniProtKB/TrEMBL
    A6JYR1, A6JYR2
    Conserved Domains (2) summary
    sd00034
    Location:150174
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl39015
    Location:167272
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...