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Prpf38a pre-mRNA processing factor 38A [ Rattus norvegicus (Norway rat) ]

Gene ID: 298374, updated on 17-Aug-2024

Summary

Official Symbol
Prpf38aprovided by RGD
Official Full Name
pre-mRNA processing factor 38Aprovided by RGD
Primary source
RGD:1311129
See related
EnsemblRapid:ENSRNOG00000009451 AllianceGenome:RGD:1311129
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311129
Summary
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of U2-type precatalytic spliceosome. Orthologous to human PRPF38A (pre-mRNA processing factor 38A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 188.4), Spleen (RPKM 138.7) and 9 other tissues See more
Orthologs
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Genomic context

See Prpf38a in Genome Data Viewer
Location:
5q34
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (128541166..128552865, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (123312461..123324160, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (128174835..128186532, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene terminal uridylyl transferase 4 Neighboring gene uncharacterized LOC134486964 Neighboring gene RNA, U6 small nuclear 67 Neighboring gene origin recognition complex, subunit 1 Neighboring gene coiled-coil and C2 domain containing 1B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of U2-type precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
pre-mRNA-splicing factor 38A
Names
PRP38 pre-mRNA processing factor 38 domain containing A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106672.1NP_001100142.1  pre-mRNA-splicing factor 38A

    See identical proteins and their annotated locations for NP_001100142.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474008
    UniProtKB/TrEMBL
    A6JYV1
    Related
    ENSRNOP00000012635.6, ENSRNOT00000012635.7
    Conserved Domains (1) summary
    pfam03371
    Location:10172
    PRP38; PRP38 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    128541166..128552865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)