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Dnali1 dynein, axonemal, light intermediate chain 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298524, updated on 17-Aug-2024

Summary

Official Symbol
Dnali1provided by RGD
Official Full Name
dynein, axonemal, light intermediate chain 1provided by RGD
Primary source
RGD:1309260
See related
EnsemblRapid:ENSRNOG00000024957 AllianceGenome:RGD:1309260
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable dynein heavy chain binding activity. Predicted to be located in ciliary base; dynein axonemal particle; and sperm flagellum. Predicted to be part of dynein complex. Predicted to be active in axoneme and filopodium. Orthologous to human DNALI1 (dynein axonemal light intermediate chain 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 158.4), Lung (RPKM 54.1) and 1 other tissue See more
Orthologs
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Genomic context

Location:
5q36
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (142603132..142611970, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (137318475..137327313, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (143053365..143062203, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene R-spondin 1 Neighboring gene uncharacterized LOC108351029 Neighboring gene G protein nucleolar 2 Neighboring gene Smad nuclear interacting protein 1 Neighboring gene MYST/Esa1-associated factor 6

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC116176

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables dynein heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables dynein heavy chain binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in sperm flagellum assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in sperm flagellum assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in 9+2 motile cilium ISO
Inferred from Sequence Orthology
more info
 
is_active_in axoneme IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in axoneme ISO
Inferred from Sequence Orthology
more info
 
located_in axoneme ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in ciliary base ISO
Inferred from Sequence Orthology
more info
 
located_in cilium ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in dynein axonemal particle ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of dynein complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in filopodium IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in filopodium ISO
Inferred from Sequence Orthology
more info
 
located_in motile cilium ISO
Inferred from Sequence Orthology
more info
 
located_in motile cilium ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in sperm flagellum ISO
Inferred from Sequence Orthology
more info
 
located_in sperm flagellum ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
axonemal dynein light intermediate polypeptide 1
Names
dynein, axonemal, light intermediate polypeptide 1
inner dynein arm light chain, axonemal

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031647.1NP_001026817.1  axonemal dynein light intermediate polypeptide 1

    See identical proteins and their annotated locations for NP_001026817.1

    Status: PROVISIONAL

    Source sequence(s)
    BC099087
    UniProtKB/Swiss-Prot
    Q4FZV3
    UniProtKB/TrEMBL
    A6IS72
    Related
    ENSRNOP00000032193.2, ENSRNOT00000029388.4
    Conserved Domains (1) summary
    pfam10211
    Location:66247
    Ax_dynein_light; Axonemal dynein light chain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    142603132..142611970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)