U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ppan peter pan homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 298699, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
Ppanprovided by RGD
Official Full Name
peter pan homologprovided by RGD
Primary source
RGD:1306325
See related
EnsemblRapid:ENSRNOG00000020608 AllianceGenome:RGD:1306325
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable rRNA binding activity. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Orthologous to several human genes including PPAN-P2RY11 (PPAN-P2RY11 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 147.7), Spleen (RPKM 126.8) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ppan in Genome Data Viewer
Location:
8q13
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (27700147..27704127)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (19423908..19427941)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (21905865..21909845)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene retinol dehydrogenase 8 Neighboring gene shiftless antiviral inhibitor of ribosomal frameshifting Neighboring gene angiopoietin-like 6 Neighboring gene small nucleolar RNA, C/D box 105B Neighboring gene small nucleolar RNA, C/D box 105 Neighboring gene eukaryotic translation initiation factor 3, subunit G Neighboring gene DNA methyltransferase 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Large-scale characterization of HeLa cell nuclear phosphoproteins. Beausoleil SA, et al. Proc Natl Acad Sci U S A, 2004 Aug 17. PMID 15302935, Free PMC Article
  2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC108837

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
suppressor of SWI4 1 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011980.1 → NP_001011980.1  suppressor of SWI4 1 homolog

    See identical proteins and their annotated locations for NP_001011980.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089842
    UniProtKB/TrEMBL
    E9PTU3, Q5FVQ2
    Related
    ENSRNOP00000027974.5, ENSRNOT00000027973.7
    Conserved Domains (2) summary
    smart00879
    Location:32 → 221
    Brix; The Brix domain is found in a number of eukaryotic proteins
    pfam04147
    Location:303 → 401
    Nop14; Nop14-like family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    27700147..27704127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039080980.2 → XP_038936908.1  suppressor of SWI4 1 homolog isoform X1

    Conserved Domains (2) summary
    smart00879
    Location:6 → 92
    Brix; The Brix domain is found in a number of eukaryotic proteins
    pfam04147
    Location:174 → 272
    Nop14; Nop14-like family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools