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Slc35f6 solute carrier family 35, member F6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298851, updated on 2-Nov-2024

Summary

Official Symbol
Slc35f6provided by RGD
Official Full Name
solute carrier family 35, member F6provided by RGD
Primary source
RGD:1309228
See related
EnsemblRapid:ENSRNOG00000009459 AllianceGenome:RGD:1309228
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
ANT2BP; RGD1309228
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and positive regulation of cell population proliferation. Predicted to be located in several cellular components, including lysosomal membrane; mitochondrion; and nucleoplasm. Predicted to be active in intracellular membrane-bounded organelle and membrane. Orthologous to human SLC35F6 (solute carrier family 35 member F6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 59.6), Brain (RPKM 56.3) and 9 other tissues See more
Orthologs
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Genomic context

See Slc35f6 in Genome Data Viewer
Location:
6q14
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (31445738..31457580, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (25725822..25737720, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (27095144..27106982, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene centromere protein A Neighboring gene uncharacterized LOC134479331 Neighboring gene uncharacterized LOC134479332 Neighboring gene potassium two pore domain channel subfamily K member 3 Neighboring gene uncharacterized LOC134479333

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
located_in lysosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier family 35 member F6
Names
ANT2-binding protein
transmembrane protein C2orf18 homolog
transport and Golgi organization 9 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017451.1NP_001017451.1  solute carrier family 35 member F6 precursor

    See identical proteins and their annotated locations for NP_001017451.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085904
    UniProtKB/Swiss-Prot
    Q5RKH7
    UniProtKB/TrEMBL
    A0A8I5ZTZ0, A6HAC9
    Related
    ENSRNOP00000012558.5, ENSRNOT00000012558.8
    Conserved Domains (1) summary
    pfam04142
    Location:106158
    Nuc_sug_transp; Nucleotide-sugar transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    31445738..31457580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261632.1XP_063117702.1  solute carrier family 35 member F6 isoform X1

    Related
    ENSRNOP00000082156.2, ENSRNOT00000095130.2