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Zfp277 zinc finger protein 277 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298977, updated on 2-Nov-2024

Summary

Official Symbol
Zfp277provided by RGD
Official Full Name
zinc finger protein 277provided by RGD
Primary source
RGD:1583856
See related
EnsemblRapid:ENSRNOG00000045854 AllianceGenome:RGD:1583856
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within cellular response to hydrogen peroxide and regulation of cellular senescence. Predicted to be located in nucleus. Orthologous to human ZNF277 (zinc finger protein 277). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 119.9), Lung (RPKM 97.6) and 9 other tissues See more
Orthologs
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Genomic context

See Zfp277 in Genome Data Viewer
Location:
6q21
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (63110609..63239941, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (57383454..57512785, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (60246209..60374388, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L29-like Neighboring gene leucine-rich single-pass membrane protein 1 Neighboring gene interferon-related developmental regulator 1 Neighboring gene uncharacterized LOC120093202 Neighboring gene dedicator of cytokinesis 4 Neighboring gene inner mitochondrial membrane peptidase subunit 2 Neighboring gene H3.3 histone like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399663.1NP_001386592.1  zinc finger protein 277

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    Related
    ENSRNOP00000067802.3, ENSRNOT00000072872.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    63110609..63239941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039078131.2XP_038934059.1  zinc finger protein 277 isoform X1