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Spin4 spindlin family, member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299038, updated on 2-Nov-2024

Summary

Symbol
Spin4provided by RGD
Full Name
spindlin family, member 4provided by RGD
Primary source
RGD:1564004
See related
EnsemblRapid:ENSRNOG00000077287 AllianceGenome:RGD:1564004
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564004; AABR07038930.1
Summary
Predicted to enable methylated histone binding activity. Predicted to be involved in negative regulation of cell population proliferation and positive regulation of canonical Wnt signaling pathway. Predicted to be located in chromatin; cytoplasm; and nucleus. Orthologous to human SPIN4 (spindlin family member 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See Spin4 in Genome Data Viewer
Location:
Xq22
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (63898338..63902427, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (59888728..59892817, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (64217074..64221225, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S10 pseudogene Neighboring gene germ cell-less 1, spermatogenesis associated, pseudogene 1 Neighboring gene Cdc42 guanine nucleotide exchange factor 9 Neighboring gene uncharacterized LOC134484135 Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables methylated histone binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in gamete generation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of canonical Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401117.1NP_001388046.1  spindlin-4

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/TrEMBL
    A0A8I6ASA7
    Related
    ENSRNOP00000104082.1, ENSRNOT00000136053.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    63898338..63902427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)