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Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299310, updated on 2-Nov-2024

Summary

Official Symbol
Ndufb11provided by RGD
Official Full Name
NADH:ubiquinone oxidoreductase subunit B11provided by RGD
Primary source
RGD:1563698
See related
EnsemblRapid:ENSRNOG00000008329 AllianceGenome:RGD:1563698
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563698
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 3 and nuclear type mitochondrial complex I deficiency 30. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 1195.3), Muscle (RPKM 904.3) and 9 other tissues See more
Orthologs
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Genomic context

See Ndufb11 in Genome Data Viewer
Location:
Xq11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (4126317..4128575)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (1572805..1575063)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (1787266..1789524)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-like modifier activating enzyme 1 Neighboring gene RNA binding motif protein 10 Neighboring gene U2 spliceosomal RNA Neighboring gene forkhead box N3, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Names
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106756.1NP_001100226.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

    See identical proteins and their annotated locations for NP_001100226.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474009
    UniProtKB/TrEMBL
    A0A8I6AUJ7, A6JZT7, D4A7L4
    Related
    ENSRNOP00000011183.4, ENSRNOT00000011183.6
    Conserved Domains (1) summary
    pfam10183
    Location:22139
    ESSS; ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    4126317..4128575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)