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Llph LLP homolog, long-term synaptic facilitation factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 299818, updated on 10-Jul-2024

Summary

Official Symbol
Llphprovided by RGD
Official Full Name
LLP homolog, long-term synaptic facilitation factorprovided by RGD
Primary source
RGD:1308261
See related
EnsemblRapid:ENSRNOG00000004316 AllianceGenome:RGD:1308261
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308261
Summary
Predicted to enable basal RNA polymerase II transcription machinery binding activity. Predicted to be involved in dendrite extension and positive regulation of dendritic spine development. Predicted to be located in chromosome. Predicted to be active in nucleolus. Orthologous to human LLPH (LLP homolog, long-term synaptic facilitation factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 164.6), Muscle (RPKM 130.7) and 9 other tissues See more
Orthologs
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Genomic context

See Llph in Genome Data Viewer
Location:
7q22
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (57620925..57625924)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (55735317..55740341)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (65004544..65009509)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene interleukin-1 receptor-associated kinase 3 Neighboring gene transmembrane BAX inhibitor motif containing 4 Neighboring gene high mobility group AT-hook 2 Neighboring gene uncharacterized LOC120093613 Neighboring gene uncharacterized LOC102549309

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables basal RNA polymerase II transcription machinery binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables basal RNA polymerase II transcription machinery binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in dendrite extension IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in dendrite extension ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of dendritic spine development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein LLP homolog
Names
LLP homolog, long-term synaptic facilitation (Aplysia)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134464.2NP_001127936.1  protein LLP homolog

    See identical proteins and their annotated locations for NP_001127936.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158738
    UniProtKB/TrEMBL
    B0BN98, F7FF98
    Conserved Domains (1) summary
    pfam10169
    Location:3117
    Laps; Learning-associated protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    57620925..57625924
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006241425.4XP_006241487.1  protein LLP homolog isoform X1

    See identical proteins and their annotated locations for XP_006241487.1

    UniProtKB/TrEMBL
    B0BN98, F7FF98
    Related
    ENSRNOP00000005794.4, ENSRNOT00000005794.8
    Conserved Domains (1) summary
    pfam10169
    Location:3117
    Laps; Learning-associated protein