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Alg13l1 ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 300284, updated on 2-Nov-2024

Summary

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Official Symbol
Alg13l1provided by RGD
Official Full Name
ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1provided by RGD
Primary source
RGD:1359416
See related
EnsemblRapid:ENSRNOG00000065758 AllianceGenome:RGD:1359416
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to act upstream of with a positive effect on protein N-linked glycosylation. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Predicted to be active in cytoplasmic side of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 36. Orthologous to human ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 77.6), Kidney (RPKM 69.5) and 9 other tissues See more
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Genomic context

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See Alg13l1 in Genome Data Viewer
Location:
Xq34
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (112681707..112702932)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (107885039..107906264)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (115561329..115589792)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein lateral stalk subunit P0, pseudogene 10 Neighboring gene ribosomal protein S26 like 5 Neighboring gene ALG13, UDP-N-acetylglucosaminyltransferase subunit Neighboring gene transient receptor potential cation channel, subfamily C, member 5 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in dolichol-linked oligosaccharide biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_positive_effect protein N-linked glycosylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of UDP-N-acetylglucosamine transferase complex ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytoplasmic side of endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
UDP-N-acetylglucosamine transferase subunit ALG13; UDP-N-acetylglucosamine transferase subunit ALG13 homolog
Names
asparagine-linked glycosylation 13 homolog
glycosyltransferase 28 domain-containing protein 1
NP_001013973.1
XP_017457442.1
XP_063135953.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013951.1 → NP_001013973.1  UDP-N-acetylglucosamine transferase subunit ALG13

    See identical proteins and their annotated locations for NP_001013973.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088233
    UniProtKB/Swiss-Prot
    Q5I0K7
    UniProtKB/TrEMBL
    A6KG91
    Related
    ENSRNOP00000068463.2, ENSRNOT00000076680.4
    Conserved Domains (1) summary
    cl10013
    Location:5 → 120
    Glycosyltransferase_GTB-type; glycosyltransferase family 1 and related proteins with GTB topology

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    112681707..112702932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017601953.3 → XP_017457442.1  UDP-N-acetylglucosamine transferase subunit ALG13 homolog isoform X1

    UniProtKB/TrEMBL
    A0A096MJN3

  2. XM_063279883.1 → XP_063135953.1  UDP-N-acetylglucosamine transferase subunit ALG13 homolog isoform X2

    UniProtKB/TrEMBL
    A6KG92
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5I0K7.1 GenPept UniProtKB/Swiss-Prot:Q5I0K7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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