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Herpud2 HERPUD family member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 300463, updated on 2-Nov-2024

Summary

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Official Symbol
Herpud2provided by RGD
Official Full Name
HERPUD family member 2provided by RGD
Primary source
RGD:1307343
See related
EnsemblRapid:ENSRNOG00000029995 AllianceGenome:RGD:1307343
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307343
Summary
Predicted to be involved in endoplasmic reticulum unfolded protein response and spermatogenesis. Predicted to be located in membrane. Orthologous to human HERPUD2 (HERPUD family member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 64.7), Thymus (RPKM 63.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Herpud2 in Genome Data Viewer
Location:
8q13
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (31849216..31894219, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (23573374..23618380, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (26266571..26311528, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene T-box transcription factor 20 Neighboring gene EH domain-containing protein 3-like Neighboring gene uncharacterized LOC108351663 Neighboring gene charged multivesicular body protein 5, pseudogene 2 Neighboring gene uncharacterized LOC120094096 Neighboring gene triosephosphate isomerase 1 like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of differentially expressed genes in mouse spermatogenesis. Pang AL, et al. J Androl, 2003 Nov-Dec. PMID 14581517
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to unfolded protein IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024988.2 → NP_001020159.2  homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8L2UM88, A6JYB6
    Related
    ENSRNOP00000100555.1, ENSRNOT00000170862.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    31849216..31894219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039081017.2 → XP_038936945.1  homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein isoform X2

    UniProtKB/Swiss-Prot
    Q66HH4

  2. XM_017595533.3 → XP_017451022.1  homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q66HH4.1 GenPept UniProtKB/Swiss-Prot:Q66HH4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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