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Ciao2a cytosolic iron-sulfur assembly component 2A [ Rattus norvegicus (Norway rat) ]

Gene ID: 300797, updated on 18-Sep-2024

Summary

Official Symbol
Ciao2aprovided by RGD
Official Full Name
cytosolic iron-sulfur assembly component 2Aprovided by RGD
Primary source
RGD:1307481
See related
EnsemblRapid:ENSRNOG00000017119 AllianceGenome:RGD:1307481
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam96a; RGD1307481
Summary
Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of CIA complex. Orthologous to human CIAO2A (cytosolic iron-sulfur assembly component 2A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 339.6), Heart (RPKM 323.2) and 9 other tissues See more
Orthologs
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Genomic context

See Ciao2a in Genome Data Viewer
Location:
8q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (75565620..75577542)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (66670533..66682455)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (71786336..71798258)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase B Neighboring gene sorting nexin 22 Neighboring gene sorting nexin 1 Neighboring gene death-associated protein kinase 2 Neighboring gene uncharacterized LOC108351731

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
cytosolic iron-sulfur assembly component 2A
Names
MIP18 family protein FAM96A
family with sequence similarity 96, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008327.1NP_001008328.1  cytosolic iron-sulfur assembly component 2A precursor

    See identical proteins and their annotated locations for NP_001008328.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086524
    UniProtKB/TrEMBL
    A0A8I6AST8, A6J5H6, F7EXH6, Q5RJS3
    Related
    ENSRNOP00000022999.4, ENSRNOT00000022999.8
    Conserved Domains (1) summary
    cl00941
    Location:39156
    FeS_assembly_P; Iron-sulfur cluster assembly protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    75565620..75577542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)