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Adgrf1 adhesion G protein-coupled receptor F1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 301266, updated on 2-Nov-2024

Summary

Symbol
Adgrf1provided by RGD
Full Name
adhesion G protein-coupled receptor F1provided by RGD
Primary source
RGD:1310285
See related
EnsemblRapid:ENSRNOG00000062544 AllianceGenome:RGD:1310285
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gpr110
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to act upstream of or within several processes, including memory; nervous system development; and positive regulation of CREB transcription factor activity. Predicted to be located in plasma membrane. Orthologous to human ADGRF1 (adhesion G protein-coupled receptor F1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 13.7), Testes (RPKM 5.8) and 3 other tissues See more
Orthologs
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Genomic context

See Adgrf1 in Genome Data Viewer
Location:
9q13
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (25158198..25210744, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (17661258..17696359, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (20343730..20378686, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene meprin A subunit alpha Neighboring gene adhesion G protein-coupled receptor F5 Neighboring gene uncharacterized LOC120094840 Neighboring gene ATP synthase membrane subunit g, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
adhesion G protein-coupled receptor F1; adhesion G-protein coupled receptor F1
Names
G protein-coupled receptor 110

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431183.1NP_001418112.1  adhesion G protein-coupled receptor F1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6AIR1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    25158198..25210744 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063267885.1XP_063123955.1  adhesion G-protein coupled receptor F1 isoform X3

  2. XM_039084503.2XP_038940431.1  adhesion G-protein coupled receptor F1 isoform X2

    Related
    ENSRNOP00000093180.1, ENSRNOT00000115168.2
    Conserved Domains (4) summary
    smart00303
    Location:531579
    GPS; G-protein-coupled receptor proteolytic site domain
    cd14964
    Location:583608
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02507
    Location:153228
    SEA; SEA domain
    cl28897
    Location:582848
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  3. XM_039084502.2XP_038940430.1  adhesion G-protein coupled receptor F1 isoform X1

    Conserved Domains (4) summary
    smart00303
    Location:537585
    GPS; G-protein-coupled receptor proteolytic site domain
    cd14964
    Location:589614
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02507
    Location:159234
    SEA; SEA domain
    cl28897
    Location:588854
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  4. XM_039084504.2XP_038940432.1  adhesion G-protein coupled receptor F1 isoform X4

    Related
    ENSRNOP00000107020.1, ENSRNOT00000140207.1
    Conserved Domains (4) summary
    smart00303
    Location:509557
    GPS; G-protein-coupled receptor proteolytic site domain
    cd14964
    Location:561586
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02507
    Location:131206
    SEA; SEA domain
    cl28897
    Location:560826
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001106894.1: Suppressed sequence

    Description
    NM_001106894.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: GPR110 (GeneID:266977).