Zdhhc9 zinc finger DHHC-type palmitoyltransferase 9 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zdhhc9provided by RGD
Official Full Name: zinc finger DHHC-type palmitoyltransferase 9provided by RGD
Primary source: RGD:1561389
See related: EnsemblRapid:ENSRNOG00000004581 AllianceGenome:RGD:1561389
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable Ras palmitoyltransferase activity. Predicted to be involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation by host of viral process; and positive regulation of defense response. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Orthologous to human ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 138.1), Lung (RPKM 113.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq36

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (132230243..132266139, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (127352340..127388245, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (135005171..135041207, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables Ras palmitoyltransferase activity	ISO Inferred from Sequence Orthology more info
enables palmitoyltransferase activity	ISO Inferred from Sequence Orthology more info
enables protein-cysteine S-palmitoyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-cysteine S-palmitoyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in peptidyl-L-cysteine S-palmitoylation	IEA Inferred from Electronic Annotation more info
involved_in peptidyl-L-cysteine S-palmitoylation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation by host of viral process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cGAS/STING signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of pyroptotic inflammatory response	ISO Inferred from Sequence Orthology more info
involved_in protein palmitoylation	ISO Inferred from Sequence Orthology more info
involved_in protein targeting to membrane	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in Golgi membrane	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
part_of palmitoyltransferase complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: palmitoyltransferase ZDHHC9

Names: membrane-associated DHHC9 zinc finger protein; zinc finger, DHHC domain containing 9; zinc finger, DHHC-type containing 9

NP_001034105.2

EC 2.3.1.225

XP_006257583.1

EC 2.3.1.225

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.