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Ccnjl cyclin J-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 303059, updated on 18-Sep-2024

Summary

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Official Symbol
Ccnjlprovided by RGD
Official Full Name
cyclin J-likeprovided by RGD
Primary source
RGD:1561384
See related
AllianceGenome:RGD:1561384
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in centrosome; cytoplasm; and nucleus. Orthologous to human CCNJL (cyclin J like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 38.4), Lung (RPKM 28.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccnjl in Genome Data Viewer
Location:
10q21
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (28497144..28554877)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (27995682..28053428)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (29122713..29181610)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 2 Neighboring gene uncharacterized LOC108352074 Neighboring gene uncharacterized LOC134480674 Neighboring gene uncharacterized LOC134480675 Neighboring gene fatty acid binding protein 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC116253

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cyclin-J-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037773.5 → NP_001032862.2  cyclin-J-like protein

    See identical proteins and their annotated locations for NP_001032862.2

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HDN1, F1LPN6
    Conserved Domains (2) summary
    cd20528
    Location:32 → 120
    CYCLIN_CCNJ-like_rpt1; first cyclin box found in cyclin-J (CCNJ) family
    cd20529
    Location:144 → 245
    CYCLIN_CCNJ-like_rpt2; second cyclin box found in cyclin-J (CCNJ) family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    28497144..28554877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063268964.1 → XP_063125034.1  cyclin-J-like protein isoform X2

  2. XM_006246133.5 → XP_006246195.1  cyclin-J-like protein isoform X1

    See identical proteins and their annotated locations for XP_006246195.1

    UniProtKB/TrEMBL
    A6HDN1, F1LPN6
    Conserved Domains (2) summary
    cd20528
    Location:32 → 120
    CYCLIN_CCNJ-like_rpt1; first cyclin box found in cyclin-J (CCNJ) family
    cd20529
    Location:144 → 245
    CYCLIN_CCNJ-like_rpt2; second cyclin box found in cyclin-J (CCNJ) family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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