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Rasl10b RAS-like, family 10, member B [ Rattus norvegicus (Norway rat) ]

Gene ID: 303382, updated on 10-Oct-2024

Summary

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Symbol
Rasl10bprovided by RGD
Full Name
RAS-like, family 10, member Bprovided by RGD
Primary source
RGD:1310873
See related
EnsemblRapid:ENSRNOG00000010302 AllianceGenome:RGD:1310873
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in positive regulation of peptide hormone secretion and regulation of systemic arterial blood pressure by atrial natriuretic peptide. Orthologous to human RASL10B (RAS like family 10 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 45.9), Heart (RPKM 27.1) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rasl10b in Genome Data Viewer
Location:
10q26
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (68707315..68719642)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (68209761..68222118)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (70626227..70639072)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 12 Neighboring gene adaptor related protein complex 2 subunit beta 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene growth arrest-specific 2 like 2 Neighboring gene similar to human chromosome 17 open reading frame 50 Neighboring gene matrix metallopeptidase 28

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein. Rybkin II, et al. J Cell Biol, 2007 Nov 5. PMID 17984325, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of peptide hormone secretion ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of systemic arterial blood pressure by atrial natriuretic peptide ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ras-like protein family member 10B
Names
ras-like protein family member 10B-like
NP_001178577.1
XP_006247090.1
XP_006247091.1
XP_008772032.1
XP_063125158.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191648.1 → NP_001178577.1  ras-like protein family member 10B

    See identical proteins and their annotated locations for NP_001178577.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A096MKD2, A6HHH6
    Conserved Domains (1) summary
    cd04142
    Location:5 → 203
    RRP22; Ras-related protein on chromosome 22 (RRP22) family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    68707315..68719642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269088.1 → XP_063125158.1  ras-like protein family member 10B isoform X2

    UniProtKB/TrEMBL
    A0A096MKD2
    Related
    ENSRNOP00000100565.1, ENSRNOT00000152884.1

  2. XM_006247029.5 → XP_006247091.1  ras-like protein family member 10B isoform X1

    See identical proteins and their annotated locations for XP_006247091.1

    UniProtKB/TrEMBL
    A0A8I6AHZ6, A6HHH6
    Conserved Domains (2) summary
    smart00173
    Location:5 → 207
    RAS; Ras subfamily of RAS small GTPases
    cl21455
    Location:5 → 235
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_006247028.5 → XP_006247090.1  ras-like protein family member 10B isoform X1

    See identical proteins and their annotated locations for XP_006247090.1

    UniProtKB/TrEMBL
    A0A8I6AHZ6, A6HHH6
    Related
    ENSRNOP00000092937.1, ENSRNOT00000117783.2
    Conserved Domains (2) summary
    smart00173
    Location:5 → 207
    RAS; Ras subfamily of RAS small GTPases
    cl21455
    Location:5 → 235
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_008773810.4 → XP_008772032.1  ras-like protein family member 10B isoform X3

    See identical proteins and their annotated locations for XP_008772032.1

    Conserved Domains (1) summary
    cl21455
    Location:50 → 181
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_010055184.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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