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Cd7 Cd7 molecule [ Rattus norvegicus (Norway rat) ]

Gene ID: 303747, updated on 2-Nov-2024

Summary

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Official Symbol
Cd7provided by RGD
Official Full Name
Cd7 moleculeprovided by RGD
Primary source
RGD:1310015
See related
EnsemblRapid:ENSRNOG00000036674 AllianceGenome:RGD:1310015
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in positive regulation of T cell cytokine production. Predicted to act upstream of or within homeostasis of number of cells within a tissue. Predicted to be located in membrane. Orthologous to human CD7 (CD7 molecule). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 198.3), Spleen (RPKM 192.2) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Cd7 in Genome Data Viewer
Location:
10q32.3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (106802373..106805269, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (106304046..106306963, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (110229931..110232812, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene dolichyl-phosphate mannosyltransferase subunit 3, regulatory, pseudogene 2 Neighboring gene solute carrier family 16 member 3 Neighboring gene casein kinase 1, delta Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene secreted and transmembrane 1B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Immunologic characterization of CD7-deficient mice. Lee DM, et al. J Immunol, 1998 Jun 15. PMID 9637484
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane signaling receptor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within homeostasis of number of cells within a tissue ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of T cell cytokine production ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
T-cell antigen CD7
Names
CD7 antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107074.1 → NP_001100544.1  T-cell antigen CD7 precursor

    See identical proteins and their annotated locations for NP_001100544.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    B2RZ54, F7F5G3
    Related
    ENSRNOP00000051817.2, ENSRNOT00000054934.6
    Conserved Domains (2) summary
    cd00096
    Location:25 → 28
    Ig; Ig strand A [structural motif]
    cl11960
    Location:27 → 125
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    106802373..106805269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086226.2 → XP_038942154.1  T-cell antigen CD7 isoform X1

    Conserved Domains (2) summary
    cd00096
    Location:12 → 17
    Ig; Ig strand C' [structural motif]
    cl11960
    Location:11 → 71
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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