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Vwa5b2 von Willebrand factor A domain containing 5B2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303812, updated on 28-Oct-2024

Summary

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Official Symbol
Vwa5b2provided by RGD
Official Full Name
von Willebrand factor A domain containing 5B2provided by RGD
Primary source
RGD:1564491
See related
EnsemblRapid:ENSRNOG00000001707 AllianceGenome:RGD:1564491
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564491
Summary
Orthologous to human VWA5B2 (von Willebrand factor A domain containing 5B2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Brain (RPKM 50.2), Thymus (RPKM 19.5) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Vwa5b2 in Genome Data Viewer
Location:
11q23
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (93810456..93827609, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (80306067..80323220, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (83991793..84008946, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene EEF1A lysine methyltransferase 4 Neighboring gene ALG3, alpha-1,3- mannosyltransferase Neighboring gene microRNA 1224 Neighboring gene uncharacterized LOC102551647 Neighboring gene ATP binding cassette subfamily F member 3 Neighboring gene uncharacterized LOC102551795 Neighboring gene adaptor related protein complex 2 subunit mu 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. Bhatnagar S, et al. J Biol Chem, 2014 Sep 5. PMID 25002582, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
von Willebrand factor A domain-containing protein 5B2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134535.1 → NP_001128007.1  von Willebrand factor A domain-containing protein 5B2 isoform 1

    See identical proteins and their annotated locations for NP_001128007.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473999
    UniProtKB/TrEMBL
    A6JSA6, D4A7U5
    Conserved Domains (3) summary
    TIGR03788
    Location:36 → 556
    marine_srt_targ; marine proteobacterial sortase target protein
    pfam13757
    Location:2 → 79
    VIT_2; Vault protein inter-alpha-trypsin domain
    pfam13768
    Location:353 → 501
    VWA_3; von Willebrand factor type A domain

  2. NM_001433292.1 → NP_001420221.1  von Willebrand factor A domain-containing protein 5B2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011

  3. NM_001433293.1 → NP_001420222.1  von Willebrand factor A domain-containing protein 5B2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    93810456..93827609 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017597972.3 → XP_017453461.1  von Willebrand factor A domain-containing protein 5B2 isoform X3

    UniProtKB/TrEMBL
    D4A7U5
    Conserved Domains (2) summary
    pfam13768
    Location:354 → 501
    VWA_3; von Willebrand factor type A domain
    pfam13757
    Location:2 → 79
    VIT_2; Vault protein inter-alpha-trypsin domain

  2. XM_017597969.3 → XP_017453458.1  von Willebrand factor A domain-containing protein 5B2 isoform X1

    UniProtKB/TrEMBL
    D4A7U5
    Conserved Domains (2) summary
    pfam13768
    Location:358 → 505
    VWA_3; von Willebrand factor type A domain
    pfam13757
    Location:2 → 79
    VIT_2; Vault protein inter-alpha-trypsin domain

  3. XM_063270480.1 → XP_063126550.1  von Willebrand factor A domain-containing protein 5B2 isoform X7

  4. XM_063270478.1 → XP_063126548.1  von Willebrand factor A domain-containing protein 5B2 isoform X1

  5. XM_063270477.1 → XP_063126547.1  von Willebrand factor A domain-containing protein 5B2 isoform X1

  6. XM_039088280.2 → XP_038944208.1  von Willebrand factor A domain-containing protein 5B2 isoform X3

    UniProtKB/TrEMBL
    D4A7U5
    Conserved Domains (2) summary
    pfam13768
    Location:354 → 501
    VWA_3; von Willebrand factor type A domain
    pfam13757
    Location:2 → 79
    VIT_2; Vault protein inter-alpha-trypsin domain

  7. XM_039088279.2 → XP_038944207.1  von Willebrand factor A domain-containing protein 5B2 isoform X2

    UniProtKB/TrEMBL
    D4A7U5
    Conserved Domains (2) summary
    pfam13768
    Location:358 → 505
    VWA_3; von Willebrand factor type A domain
    pfam13757
    Location:2 → 79
    VIT_2; Vault protein inter-alpha-trypsin domain

  8. XM_063270479.1 → XP_063126549.1  von Willebrand factor A domain-containing protein 5B2 isoform X4

    Related
    ENSRNOP00000035500.7, ENSRNOT00000037612.7

  9. XM_017597974.3 → XP_017453463.1  von Willebrand factor A domain-containing protein 5B2 isoform X5

    UniProtKB/TrEMBL
    D4A7U5
    Conserved Domains (1) summary
    pfam13768
    Location:134 → 282
    VWA_3; von Willebrand factor type A domain

  10. XM_006248571.3 → XP_006248633.1  von Willebrand factor A domain-containing protein 5B2 isoform X5

    UniProtKB/TrEMBL
    D4A7U5
    Conserved Domains (1) summary
    pfam13768
    Location:134 → 282
    VWA_3; von Willebrand factor type A domain

  11. XM_039088283.2 → XP_038944211.1  von Willebrand factor A domain-containing protein 5B2 isoform X6

    Conserved Domains (2) summary
    pfam13768
    Location:358 → 505
    VWA_3; von Willebrand factor type A domain
    pfam13757
    Location:2 → 79
    VIT_2; Vault protein inter-alpha-trypsin domain

  12. XM_063270481.1 → XP_063126551.1  von Willebrand factor A domain-containing protein 5B2 isoform X8

  13. XM_039088284.2 → XP_038944212.1  von Willebrand factor A domain-containing protein 5B2 isoform X9

    Conserved Domains (2) summary
    pfam13768
    Location:358 → 505
    VWA_3; von Willebrand factor type A domain
    pfam13757
    Location:2 → 79
    VIT_2; Vault protein inter-alpha-trypsin domain

RNA

  1. XR_005491021.2 RNA Sequence

  2. XR_010055951.1 RNA Sequence

  3. XR_010055950.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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