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Filip1l filamin A interacting protein 1-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 304020, updated on 2-Nov-2024

Summary

Official Symbol
Filip1lprovided by RGD
Official Full Name
filamin A interacting protein 1-likeprovided by RGD
Primary source
RGD:1565927
See related
EnsemblRapid:ENSRNOG00000001645 AllianceGenome:RGD:1565927
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565927
Summary
Predicted to be involved in protein localization to actin cytoskeleton. Predicted to be active in actin cytoskeleton. Orthologous to human FILIP1L (filamin A interacting protein 1 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 190.1), Heart (RPKM 159.1) and 9 other tissues See more
Orthologs
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Genomic context

See Filip1l in Genome Data Viewer
Location:
11q12
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (56403467..56646422, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (42937353..43177085, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (45039488..45275141, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene collagen type VIII alpha 1 chain Neighboring gene cms1 ribosomal small subunit homolog Neighboring gene uncharacterized LOC134481062 Neighboring gene uncharacterized LOC134481063 Neighboring gene transmembrane protein 30C

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein localization to actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
filamin A-interacting protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427234.1NP_001414163.1  filamin A-interacting protein 1-like

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    Related
    ENSRNOP00000045927.4, ENSRNOT00000046383.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    56403467..56646422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017598112.3XP_017453601.2  filamin A-interacting protein 1-like isoform X1

  2. XM_063270563.1XP_063126633.1  filamin A-interacting protein 1-like isoform X3

  3. XM_063270564.1XP_063126634.1  filamin A-interacting protein 1-like isoform X3

  4. XM_039088830.2XP_038944758.1  filamin A-interacting protein 1-like isoform X2

    UniProtKB/TrEMBL
    D4A900
    Conserved Domains (2) summary
    COG1196
    Location:227811
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09727
    Location:64284
    CortBP2; Cortactin-binding protein-2