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Dop1b DOP1 leucine zipper like protein B [ Rattus norvegicus (Norway rat) ]

Gene ID: 304077, updated on 17-Aug-2024

Summary

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Official Symbol
Dop1bprovided by RGD
Official Full Name
DOP1 leucine zipper like protein Bprovided by RGD
Primary source
RGD:1306097
See related
EnsemblRapid:ENSRNOG00000051204 AllianceGenome:RGD:1306097
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Dopey2; RGD1306097
Summary
Predicted to be involved in cognition. Predicted to be located in early endosome membrane. Predicted to be active in endosome and trans-Golgi network. Orthologous to human DOP1B (DOP1 leucine zipper like protein B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 64.1), Lung (RPKM 63.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Dop1b in Genome Data Viewer
Location:
11q11
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (46494058..46595601)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (33024376..33125931)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (33929142..34027447)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene carbonyl reductase 1 like 3 Neighboring gene carbonyl reductase 3 Neighboring gene interferon induced transmembrane protein3, pseudogene 2 Neighboring gene MORC family CW-type zinc finger 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Swaminathan S, et al. PLoS One, 2012. PMID 23227193, Free PMC Article
  2. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Gonzalez-Begne M, et al. J Proteome Res, 2009 Mar. PMID 19199708, Free PMC Article
  3. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
  4. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Golgi to endosome transport IEA
Inferred from Electronic Annotation
more info
  
involved_in cognition ISO
Inferred from Sequence Orthology
more info
  
involved_in embryonic pattern specification ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in early endosome membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein dopey-2
Names
dopey family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191660.2 → NP_001178589.2  protein dopey-2

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000011
    UniProtKB/TrEMBL
    A0A0G2JXD9
    Related
    ENSRNOP00000070233.3, ENSRNOT00000083594.3
    Conserved Domains (2) summary
    pfam04118
    Location:13 → 304
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:1948 → 2096
    Dopey_N; Dopey, N-terminal

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    46494058..46595601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039088417.2 → XP_038944345.1  protein dopey-2 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JXD9
    Related
    ENSRNOP00000100103.1, ENSRNOT00000148794.1
    Conserved Domains (2) summary
    pfam04118
    Location:13 → 304
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:1960 → 2108
    Dopey_N; Dopey, N-terminal

RNA

  1. XR_005491035.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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