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Sbno1 strawberry notch homolog 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304470, updated on 13-Apr-2024

Summary

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Official Symbol
Sbno1provided by RGD
Official Full Name
strawberry notch homolog 1provided by RGD
Primary source
RGD:1310005
See related
Ensembl:ENSRNOG00000001064 AllianceGenome:RGD:1310005
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable chromatin DNA binding activity and histone binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human SBNO1 (strawberry notch homolog 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 184.1), Kidney (RPKM 179.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Sbno1 in Genome Data Viewer
Location:
12q15
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (37835306..37895861)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (32175176..32234200)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (37593692..37650761)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene Rab interacting lysosomal protein-like 2 Neighboring gene lysine methyltransferase 5A Neighboring gene cyclin-dependent kinase 2 associated protein 1 Neighboring gene mitochondrial translation release factor in rescue

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth. Mertz J, et al. Mol Cell Proteomics, 2015 Jul. PMID 25931508, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables chromatin DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein strawberry notch homolog 1
Names
sno, strawberry notch homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001389247.1 → NP_001376176.1  protein strawberry notch homolog 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/Swiss-Prot
    Q5BJL5
    UniProtKB/TrEMBL
    A0A0G2K3C0, F1LS26
    Related
    ENSRNOP00000054711.4, ENSRNOT00000057902.4
    Conserved Domains (2) summary
    pfam13871
    Location:871 → 1147
    Helicase_C_4; C-terminal domain on Strawberry notch homolog
    pfam13872
    Location:257 → 559
    AAA_34; P-loop containing NTP hydrolase pore-1

  2. NM_001389248.1 → NP_001376177.1  protein strawberry notch homolog 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/Swiss-Prot
    Q5BJL5
    UniProtKB/TrEMBL
    A0A0G2K3C0, A0A8I6ATT9
    Related
    ENSRNOP00000097893.1, ENSRNOT00000102429.1
    Conserved Domains (2) summary
    pfam13871
    Location:836 → 1112
    Helicase_C_4; C-terminal domain on Strawberry notch homolog
    pfam13872
    Location:222 → 524
    AAA_34; P-loop containing NTP hydrolase pore-1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    37835306..37895861
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089440.2 → XP_038945368.1  protein strawberry notch homolog 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5BJL5
    UniProtKB/TrEMBL
    A0A0G2K3C0

  2. XM_039089441.2 → XP_038945369.1  protein strawberry notch homolog 1 isoform X2

    UniProtKB/Swiss-Prot
    Q5BJL5
    UniProtKB/TrEMBL
    A0A0G2K3C0
    Conserved Domains (2) summary
    pfam13871
    Location:870 → 1146
    Helicase_C_4; C-terminal domain on Strawberry notch homolog
    pfam13872
    Location:256 → 558
    AAA_34; P-loop containing NTP hydrolase pore-1

  3. XM_006249301.5 → XP_006249363.1  protein strawberry notch homolog 1 isoform X3

    UniProtKB/Swiss-Prot
    Q5BJL5
    UniProtKB/TrEMBL
    A0A0G2K3C0
    Conserved Domains (2) summary
    pfam13871
    Location:870 → 1146
    Helicase_C_4; C-terminal domain on Strawberry notch homologue
    pfam13872
    Location:256 → 558
    AAA_34; P-loop containing NTP hydrolase pore-1

  4. XM_039089442.2 → XP_038945370.1  protein strawberry notch homolog 1 isoform X4

    UniProtKB/Swiss-Prot
    Q5BJL5
    UniProtKB/TrEMBL
    A0A0G2K3C0
    Conserved Domains (2) summary
    pfam13871
    Location:836 → 1112
    Helicase_C_4; C-terminal domain on Strawberry notch homolog
    pfam13872
    Location:222 → 524
    AAA_34; P-loop containing NTP hydrolase pore-1

  5. XM_039089443.2 → XP_038945371.1  protein strawberry notch homolog 1 isoform X5

    UniProtKB/Swiss-Prot
    Q5BJL5
    UniProtKB/TrEMBL
    A0A0G2K3C0
    Conserved Domains (2) summary
    pfam13871
    Location:835 → 1111
    Helicase_C_4; C-terminal domain on Strawberry notch homolog
    pfam13872
    Location:221 → 523
    AAA_34; P-loop containing NTP hydrolase pore-1

  6. XM_063271301.1 → XP_063127371.1  protein strawberry notch homolog 1 isoform X1

  7. XM_063271302.1 → XP_063127372.1  protein strawberry notch homolog 1 isoform X2

  8. XM_039089444.2 → XP_038945372.1  protein strawberry notch homolog 1 isoform X6

    UniProtKB/Swiss-Prot
    Q5BJL5
    Conserved Domains (2) summary
    pfam13871
    Location:665 → 941
    Helicase_C_4; C-terminal domain on Strawberry notch homolog
    pfam13872
    Location:51 → 353
    AAA_34; P-loop containing NTP hydrolase pore-1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001107138.1: Suppressed sequence

    Description
    NM_001107138.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BJL5.2 GenPept UniProtKB/Swiss-Prot:Q5BJL5

Gene LinkOut

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Chemical Information
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Research Materials
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