c3a.2 - complement C3a, tandem duplicate 2

Predicted to enable endopeptidase inhibitor activity. Acts upstream of or within cellular response to estrogen stimulus. Predicted to be located in extracellular space. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; sickle cell anemia; and silicosis. Orthologous to human C3 (complement C3). [provided by Alliance of Genome Resources, Apr 2022]

NCBI Orthologs

How was this calculated?