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Fcrla Fc receptor-like A [ Rattus norvegicus (Norway rat) ]

Gene ID: 304965, updated on 2-Nov-2024

Summary

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Official Symbol
Fcrlaprovided by RGD
Official Full Name
Fc receptor-like Aprovided by RGD
Primary source
RGD:1306176
See related
EnsemblRapid:ENSRNOG00000003136 AllianceGenome:RGD:1306176
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fcrlm1; RGD1306176
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway and immune response. Predicted to be located in cytoplasm. Predicted to be active in external side of plasma membrane. Orthologous to human FCRLA (Fc receptor like A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 297.2), Thymus (RPKM 32.4) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fcrla in Genome Data Viewer
Location:
13q24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (85693177..85702875, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (83160453..83170170, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (89296570..89306219, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096314 Neighboring gene Fc receptor-like B Neighboring gene U1 spliceosomal RNA Neighboring gene Fc gamma receptor 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A new Fc receptor homolog, FREB2, found in germinal center B cells. Wilson TJ, et al. Genes Immun, 2005 Jun. PMID 15815692
  2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Fc receptor-like A
Names
Fc receptor homolog expressed in B cells
fc receptor-like and mucin-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100682.1 → NP_001094152.1  Fc receptor-like A precursor

    See identical proteins and their annotated locations for NP_001094152.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158820
    UniProtKB/Swiss-Prot
    Q3B8P2
    UniProtKB/TrEMBL
    A6IDQ8, B0BNH2
    Related
    ENSRNOP00000004183.5, ENSRNOT00000004183.8
    Conserved Domains (3) summary
    smart00410
    Location:98 → 172
    IG_like; Immunoglobulin like
    pfam13927
    Location:178 → 249
    Ig_3; Immunoglobulin domain
    cl11960
    Location:86 → 172
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    85693177..85702875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039090795.2 → XP_038946723.1  Fc receptor-like A isoform X1

    UniProtKB/TrEMBL
    A6IDQ8, A6IDQ9
    Conserved Domains (3) summary
    smart00409
    Location:190 → 258
    IG; Immunoglobulin
    cd00096
    Location:86 → 90
    Ig; Ig strand A [structural motif]
    cl11960
    Location:86 → 172
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3B8P2.2 GenPept UniProtKB/Swiss-Prot:Q3B8P2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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