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Kif26b kinesin family member 26B [ Rattus norvegicus (Norway rat) ]

Gene ID: 305012, updated on 2-Nov-2024

Summary

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Official Symbol
Kif26bprovided by RGD
Official Full Name
kinesin family member 26Bprovided by RGD
Primary source
RGD:1560022
See related
EnsemblRapid:ENSRNOG00000028624 AllianceGenome:RGD:1560022
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560022; RGD1560572
Summary
Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to act upstream of or within establishment of cell polarity; positive regulation of cell-cell adhesion; and ureteric bud invasion. Predicted to be located in cytoplasm and cytoskeleton. Orthologous to human KIF26B (kinesin family member 26B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 43.3), Kidney (RPKM 20.2) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Kif26b in Genome Data Viewer
Location:
13q26
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (92815427..93221071)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (90282821..90689058)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (96775356..97173469, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene EF-hand calcium binding domain 2 Neighboring gene eukaryotic translation elongation factor 1 gamma, pseudogene 1 Neighboring gene uncharacterized LOC134481603 Neighboring gene uncharacterized LOC134481536 Neighboring gene uncharacterized LOC134481605 Neighboring gene uncharacterized LOC134481604 Neighboring gene uncharacterized LOC108352580 Neighboring gene uncharacterized LOC108352579 Neighboring gene SET and MYND domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. An enhancer-trap LacZ transgene reveals a distinct expression pattern of Kinesin family 26B in mouse embryos. Marikawa Y, et al. Dev Genes Evol, 2004 Feb. PMID 14727108
  2. Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Uchiyama Y, et al. Proc Natl Acad Sci U S A, 2010 May 18. PMID 20439720, Free PMC Article
  3. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Expression analysis of a related gene in mouse.
    Title: An enhancer-trap LacZ transgene reveals a distinct expression pattern of Kinesin family 26B in mouse embryos.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within establishment of cell polarity ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within ureteric bud invasion ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
kinesin-like protein KIF26B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109079.3 → NP_001102549.2  kinesin-like protein KIF26B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/TrEMBL
    D4ADC4
    Related
    ENSRNOP00000017784.7, ENSRNOT00000017784.8
    Conserved Domains (2) summary
    smart00129
    Location:451 → 798
    KISc; Kinesin motor, catalytic domain. ATPase
    cd00106
    Location:450 → 798
    KISc; Kinesin motor domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    92815427..93221071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063272386.1 → XP_063128456.1  kinesin-like protein KIF26B isoform X1

  2. XM_063272387.1 → XP_063128457.1  kinesin-like protein KIF26B isoform X2

  3. XM_063272388.1 → XP_063128458.1  kinesin-like protein KIF26B isoform X2

  4. XM_039090818.2 → XP_038946746.1  kinesin-like protein KIF26B isoform X3

    UniProtKB/TrEMBL
    A6JGF1
    Conserved Domains (2) summary
    PHA03307
    Location:1319 → 1610
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00106
    Location:68 → 416
    KISc; Kinesin motor domain
Nucleotide Protein Strain
Heading Accession and Version

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