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Kctd3 potassium channel tetramerization domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305055, updated on 2-Nov-2024

Summary

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Official Symbol
Kctd3provided by RGD
Official Full Name
potassium channel tetramerization domain containing 3provided by RGD
Primary source
RGD:1310658
See related
EnsemblRapid:ENSRNOG00000002627 AllianceGenome:RGD:1310658
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ren-45
Summary
Predicted to be involved in protein homooligomerization. Predicted to be located in plasma membrane. Orthologous to human KCTD3 (potassium channel tetramerization domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 163.4), Kidney (RPKM 125.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Kctd3 in Genome Data Viewer
Location:
13q26
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (103041488..103080069, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (100510193..100548765, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (107433588..107471843, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene usherin Neighboring gene uncharacterized LOC134481543 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102548492 Neighboring gene uncharacterized LOC102548648 Neighboring gene transmembrane protein 14C like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3). Cao-Ehlker X, et al. J Biol Chem, 2013 Mar 15. PMID 23382386, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein homooligomerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
BTB/POZ domain-containing protein KCTD3
Names
potassium channel tetramerisation domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107199.1 → NP_001100669.1  BTB/POZ domain-containing protein KCTD3

    See identical proteins and their annotated locations for NP_001100669.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473985
    UniProtKB/TrEMBL
    A0A8I6A9V0, A6JGV1
    Related
    ENSRNOP00000003556.8, ENSRNOT00000003556.8
    Conserved Domains (2) summary
    smart00225
    Location:20 → 114
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam02214
    Location:20 → 105
    BTB_2; BTB/POZ domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    103041488..103080069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039090826.2 → XP_038946754.1  BTB/POZ domain-containing protein KCTD3 isoform X1

    UniProtKB/TrEMBL
    D3ZNX0
    Conserved Domains (1) summary
    cl38908
    Location:17 → 119
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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