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Fcrl6 Fc receptor-like 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305103, updated on 2-Nov-2024

Summary

Official Symbol
Fcrl6provided by RGD
Official Full Name
Fc receptor-like 6provided by RGD
Primary source
RGD:1563939
See related
EnsemblRapid:ENSRNOG00000000055 AllianceGenome:RGD:1563939
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gp42
Summary
Predicted to enable MHC class II protein binding activity; protein phosphatase binding activity; and transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway and immune response. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Orthologous to human FCRL6 (Fc receptor like 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 3.7), Heart (RPKM 3.0) and 7 other tissues See more
Orthologs
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Genomic context

See Fcrl6 in Genome Data Viewer
Location:
13q24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (87595058..87604657, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (85062709..85072308, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (90982814..90992415, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene V-set and immunoglobulin domain containing 8 Neighboring gene SLAM family member 8 Neighboring gene dual specificity phosphatase 23 Neighboring gene C-reactive protein

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables MHC class II protein binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cell surface glycoprotein gp42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164726.1NP_001158198.1  cell surface glycoprotein gp42 precursor

    See identical proteins and their annotated locations for NP_001158198.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/Swiss-Prot
    P23505
    Related
    ENSRNOP00000101561.1, ENSRNOT00000135709.1
    Conserved Domains (3) summary
    smart00410
    Location:3199
    IG_like; Immunoglobulin like
    pfam13895
    Location:23106
    Ig_2; Immunoglobulin domain
    pfam13927
    Location:115188
    Ig_3; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    87595058..87604657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)