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Trmt44 tRNA methyltransferase 44 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305443, updated on 2-Nov-2024

Summary

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Official Symbol
Trmt44provided by RGD
Official Full Name
tRNA methyltransferase 44provided by RGD
Primary source
RGD:1308380
See related
EnsemblRapid:ENSRNOG00000008898 AllianceGenome:RGD:1308380
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mettl19; RGD1308380
Summary
Predicted to enable tRNA (uridine) methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be located in cytoplasm. Orthologous to human TRMT44 (tRNA methyltransferase 44 homolog). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 47.6), Liver (RPKM 46.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Trmt44 in Genome Data Viewer
Location:
14q21
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (79399943..79424761)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (75175331..75204291)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (80361490..80379408)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene SH3 domain and tetratricopeptide repeats 1 Neighboring gene HtrA serine peptidase 3 Neighboring gene acyl-CoA oxidase 3, pristanoyl Neighboring gene carboxypeptidase Z Neighboring gene uncharacterized LOC120096640

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables tRNA (uridine) methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable tRNA (uracil-O(2)-)-methyltransferase
Names
methyltransferase like 19
tRNA methyltransferase 44 homolog
NP_001123533.1
XP_038947891.2
XP_038947892.2
XP_038947893.1
XP_038947894.1
XP_038947895.1
XP_038947896.2
XP_038947898.1
XP_038947899.2
XP_063129221.1
XP_063129222.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130061.1 → NP_001123533.1  probable tRNA (uracil-O(2)-)-methyltransferase

    See identical proteins and their annotated locations for NP_001123533.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473963
    UniProtKB/TrEMBL
    A6IJZ6, D3ZS79
    Related
    ENSRNOP00000011824.4, ENSRNOT00000011824.8
    Conserved Domains (1) summary
    pfam07757
    Location:242 → 353
    AdoMet_MTase; Predicted AdoMet-dependent methyltransferase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    79399943..79424761
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039091965.2 → XP_038947893.1  probable tRNA (uracil-O(2)-)-methyltransferase isoform X3

    Conserved Domains (1) summary
    pfam07757
    Location:67 → 178
    AdoMet_MTase; Predicted AdoMet-dependent methyltransferase

  2. XM_039091967.2 → XP_038947895.1  probable tRNA (uracil-O(2)-)-methyltransferase isoform X4

    Conserved Domains (1) summary
    pfam07757
    Location:55 → 166
    AdoMet_MTase; Predicted AdoMet-dependent methyltransferase

  3. XM_039091963.2 → XP_038947891.2  probable tRNA (uracil-O(2)-)-methyltransferase isoform X1

    Related
    ENSRNOP00000088869.2, ENSRNOT00000101643.2

  4. XM_039091964.2 → XP_038947892.2  probable tRNA (uracil-O(2)-)-methyltransferase isoform X2

  5. XM_063273151.1 → XP_063129221.1  probable tRNA (uracil-O(2)-)-methyltransferase isoform X2

  6. XM_063273152.1 → XP_063129222.1  probable tRNA (uracil-O(2)-)-methyltransferase isoform X2

  7. XM_039091971.2 → XP_038947899.2  probable tRNA (uracil-O(2)-)-methyltransferase isoform X7

  8. XM_039091968.2 → XP_038947896.2  probable tRNA (uracil-O(2)-)-methyltransferase isoform X5

  9. XM_039091966.2 → XP_038947894.1  probable tRNA (uracil-O(2)-)-methyltransferase isoform X4

    Conserved Domains (1) summary
    pfam07757
    Location:55 → 166
    AdoMet_MTase; Predicted AdoMet-dependent methyltransferase

  10. XM_039091970.2 → XP_038947898.1  probable tRNA (uracil-O(2)-)-methyltransferase isoform X6

    Conserved Domains (1) summary
    pfam07757
    Location:38 → 125
    AdoMet_MTase; Predicted AdoMet-dependent methyltransferase
Nucleotide Protein Strain
Heading Accession and Version

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