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Ccser2 coiled-coil serine-rich protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306306, updated on 2-Nov-2024

Summary

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Official Symbol
Ccser2provided by RGD
Official Full Name
coiled-coil serine-rich protein 2provided by RGD
Primary source
RGD:1304626
See related
EnsemblRapid:ENSRNOG00000022781 AllianceGenome:RGD:1304626
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gcap14; Fam190b; RGD1304626
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in microtubule bundle formation. Predicted to be active in microtubule cytoskeleton. Orthologous to human CCSER2 (coiled-coil serine rich protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 290.9), Muscle (RPKM 241.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccser2 in Genome Data Viewer
Location:
16p14
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (12633374..12746045, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (12613103..12725764, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (14090547..14210512, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene tumor protein, translationally-controlled 1 like 2 Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA15 Neighboring gene uncharacterized LOC134482323 Neighboring gene retinal G protein coupled receptor Neighboring gene leucine-rich repeat, Ig-like and transmembrane domains 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The murine Gcap14 gene encodes a novel microtubule binding and bundling protein. Hosono H, et al. FEBS Lett, 2012 May 21. PMID 22673506
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in microtubule bundle formation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within microtubule bundle formation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
serine-rich coiled-coil domain-containing protein 2
Names
family with sequence similarity 190, member B
granule cell antiserum positive 14
protein FAM190B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427501.1 → NP_001414430.1  serine-rich coiled-coil domain-containing protein 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    D4A4E5
    Related
    ENSRNOP00000016494.8, ENSRNOT00000016494.9

  2. NM_001427502.1 → NP_001414431.1  serine-rich coiled-coil domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A0A8I6A5N0, A6K9I4
    Related
    ENSRNOP00000086338.1, ENSRNOT00000106370.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    12633374..12746045 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600329.3 → XP_017455818.2  serine-rich coiled-coil domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A5N0, A6K9I4

  2. XM_039095013.2 → XP_038950941.1  serine-rich coiled-coil domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A6K9I5

  3. XM_039095014.2 → XP_038950942.1  serine-rich coiled-coil domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A6K9I5

  4. XM_039095016.2 → XP_038950944.1  serine-rich coiled-coil domain-containing protein 2 isoform X6

  5. XM_039095015.2 → XP_038950943.1  serine-rich coiled-coil domain-containing protein 2 isoform X6

  6. XM_063275367.1 → XP_063131437.1  serine-rich coiled-coil domain-containing protein 2 isoform X3

  7. XM_063275366.1 → XP_063131436.1  serine-rich coiled-coil domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I6GG47
    Related
    ENSRNOP00000077902.2, ENSRNOT00000098179.2

  8. XM_063275368.1 → XP_063131438.1  serine-rich coiled-coil domain-containing protein 2 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

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