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psme3 proteasome activator subunit 3 [ Danio rerio (zebrafish) ]

Gene ID: 30649, updated on 12-Sep-2024

Summary

Official Symbol
psme3provided by ZNC
Official Full Name
proteasome activator subunit 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-991110-19
See related
Ensembl:ENSDARG00000012234 AllianceGenome:ZFIN:ZDB-GENE-991110-19
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
unp310; PA28-gamma; wu:fb19c08
Summary
Predicted to enable endopeptidase activator activity. Acts upstream of or within sprouting angiogenesis. Predicted to be part of proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human PSME3 (proteasome activator subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See psme3 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (27206738..27212835, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (27115378..27121475, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene si:busm1-227h09.4, pseudogene Neighboring gene uncharacterized LOC100535964 Neighboring gene microRNA 10a Neighboring gene homeobox B1b Neighboring gene src kinase associated phosphoprotein 1 Neighboring gene NBR1 autophagy cargo receptor a Neighboring gene uncharacterized LOC110440144 Neighboring gene transmembrane protein 106A

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables endopeptidase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in positive regulation of endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of proteasomal protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within sprouting angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of proteasome activator complex IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
proteasome activator complex subunit 3
Names
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131376.2NP_571451.2  proteasome activator complex subunit 3

    See identical proteins and their annotated locations for NP_571451.2

    Status: PROVISIONAL

    Source sequence(s)
    BC045495
    UniProtKB/TrEMBL
    A0A0R4ICU4, A0A8N7XJK1, Q6NWK5, Q7ZU20
    Related
    ENSDARP00000005578.7, ENSDART00000002835.9
    Conserved Domains (2) summary
    pfam02251
    Location:1268
    PA28_alpha; Proteasome activator pa28 alpha subunit
    pfam02252
    Location:113253
    PA28_beta; Proteasome activator pa28 beta subunit

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    27206738..27212835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394847.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    110854..116951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)