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fgfr1a - fibroblast growth factor receptor 1a

Enables fibroblast growth factor receptor activity. Acts upstream of or within several processes, including fin regeneration; negative regulation of endodermal cell fate specification; and nervous system development. Predicted to be located in several cellular components, including Golgi apparatus; cytoplasmic vesicle; and cytosol. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including embryonic structure; head; intestine; nervous system; and trunk vasculature. Human ortholog(s) of this gene implicated in several diseases, including Jackson-Weiss syndrome; bone disease (multiple); carcinoma (multiple); hematologic cancer (multiple); and hypogonadotropic hypogonadism (multiple). Orthologous to human FGFR1 (fibroblast growth factor receptor 1). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to fgfr1a

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Species Gene Architecture aa