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Ifgga2l1 interferon-gamma-inducible GTPase 2 like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307414, updated on 2-Nov-2024

Summary

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Official Symbol
Ifgga2l1provided by RGD
Official Full Name
interferon-gamma-inducible GTPase 2 like 1provided by RGD
Primary source
RGD:1359421
See related
EnsemblRapid:ENSRNOG00000019542 AllianceGenome:RGD:1359421
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ifgga3; Ifgga2l
Summary
Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly; cellular response to interferon-beta; and innate immune response. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 371.6), Thymus (RPKM 288.8) and 8 other tissues See more
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Genomic context

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See Ifgga2l1 in Genome Data Viewer
Location:
18q12.1
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (56031907..56040627)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (53761118..53770183)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (55576239..55584959)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL13-like Neighboring gene similar to interferon-inducible GTPase Neighboring gene interferon-inducible GTPase 1-like Neighboring gene interferon-gamma-inducible GTPase 2 like, pseudogene 2 Neighboring gene interferon-gamma-inducible GTPase 4 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC108823

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to interferon-beta IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
interferon-gamma-inducible GTPase 2 like 1
Names
Interferon-inducible GTPase 1
interferon-gamma-inducible GTPase Ifgga3 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012353.1 → NP_001012353.1  interferon-gamma-inducible GTPase 2 like 1

    See identical proteins and their annotated locations for NP_001012353.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089836
    UniProtKB/TrEMBL
    F7F0H6, Q5FVQ6
    Related
    ENSRNOP00000082693.1, ENSRNOT00000117683.2
    Conserved Domains (3) summary
    cd04104
    Location:68 → 264
    p47_IIGP_like; p47 GTPase family includes IGTP, TGTP/Mg21, IRG-47, GTPI, LRG-47, and IIGP1
    pfam05049
    Location:34 → 408
    IIGP; Interferon-inducible GTPase (IIGP)
    cl21455
    Location:20 → 90
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    56031907..56040627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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