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RGD1309362 similar to interferon-inducible GTPase [ Rattus norvegicus (Norway rat) ]

Gene ID: 307415, updated on 2-Nov-2024

Summary

Official Symbol
RGD1309362provided by RGD
Official Full Name
similar to interferon-inducible GTPaseprovided by RGD
Primary source
RGD:1309362
See related
EnsemblRapid:ENSRNOG00000081104 AllianceGenome:RGD:1309362
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ifgga1
Summary
Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly; cellular response to interferon-beta; and innate immune response. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 51.0), Thymus (RPKM 38.5) and 8 other tissues See more
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Genomic context

See RGD1309362 in Genome Data Viewer
Location:
18q12.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (55943741..55969375)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (55483059..55508714)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene ferritin heavy chain-like Neighboring gene uncharacterized LOC102548951 Neighboring gene large ribosomal subunit protein eL13-like Neighboring gene interferon-inducible GTPase 1-like Neighboring gene interferon-gamma-inducible GTPase 2 like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC116227

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cellular response to interferon-beta IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
similar to interferon-inducible GTPase; uncharacterized protein LOC307415
Names
interferon-gamma-inducible GTPase Ifgga1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024884.2NP_001020055.1  similar to interferon-inducible GTPase

    See identical proteins and their annotated locations for NP_001020055.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    F7F0H6, Q4V797
    Related
    ENSRNOP00000102395.1, ENSRNOT00000126135.1
    Conserved Domains (2) summary
    cd04104
    Location:68264
    p47_IIGP_like; p47 GTPase family includes IGTP, TGTP/Mg21, IRG-47, GTPI, LRG-47, and IIGP1
    pfam05049
    Location:34408
    IIGP; Interferon-inducible GTPase (IIGP)
  2. NM_001429145.1NP_001416074.1  similar to interferon-inducible GTPase

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    Q4V797

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    55943741..55969375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063277357.1XP_063133427.1  uncharacterized protein LOC307415 isoform X1

    Related
    ENSRNOP00000108942.1, ENSRNOT00000126462.1