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Nol4 nucleolar protein 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307553, updated on 17-Aug-2024

Summary

Official Symbol
Nol4provided by RGD
Official Full Name
nucleolar protein 4provided by RGD
Primary source
RGD:1310663
See related
EnsemblRapid:ENSRNOG00000014775 AllianceGenome:RGD:1310663
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in nucleolus. Orthologous to human NOL4 (nucleolar protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 83.6), Testes (RPKM 22.5) and 1 other tissue See more
Orthologs
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Genomic context

Location:
18p12
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (14207303..14569697, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (13932499..14294873, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (13658260..14016713, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene ASXL transcriptional regulator 3 Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC120098257 Neighboring gene cytochrome b5 type A, pseudogene 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene dystrobrevin, alpha Neighboring gene uncharacterized LOC120098123

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107401.1NP_001100871.1  nucleolar protein 4 isoform 1

    See identical proteins and their annotated locations for NP_001100871.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473974
    UniProtKB/TrEMBL
    A6J2I2
    Related
    ENSRNOP00000107260.1, ENSRNOT00000131803.1
  2. NM_001415694.1NP_001402623.1  nucleolar protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    D4A3P4
    Related
    ENSRNOP00000038969.4, ENSRNOT00000041125.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    14207303..14569697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096914.2XP_038952842.1  nucleolar protein 4 isoform X3

    Related
    ENSRNOP00000104273.1, ENSRNOT00000154299.1
    Conserved Domains (2) summary
    pfam17921
    Location:110164
    Integrase_H2C2; Integrase zinc binding domain
    NF033845
    Location:208414
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
  2. XM_039096918.2XP_038952846.1  nucleolar protein 4 isoform X8

    Conserved Domains (1) summary
    NF033845
    Location:229400
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
  3. XM_017600973.3XP_017456462.1  nucleolar protein 4 isoform X1

  4. XM_063277444.1XP_063133514.1  nucleolar protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8I6ADW2
    Related
    ENSRNOP00000090479.1, ENSRNOT00000103441.2
  5. XM_039096915.2XP_038952843.1  nucleolar protein 4 isoform X4

    Conserved Domains (2) summary
    pfam17921
    Location:1550
    Integrase_H2C2; Integrase zinc binding domain
    NF033845
    Location:94265
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
  6. XM_017600974.3XP_017456463.1  nucleolar protein 4 isoform X5

  7. XM_017600975.3XP_017456464.1  nucleolar protein 4 isoform X6

  8. XM_039096917.2XP_038952845.1  nucleolar protein 4 isoform X7